Impact of Conformational Effects on the Ring–Chain Equilibrium of Hydrogen-Bonded Dinucleosides

Carlos Montoro-García, Nerea Bilbao, Iris M. Tsagri, Francesco Zaccaria, Maria J. Mayoral, Célia Fonseca Guerra*, David González-Rodríguez

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

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Abstract

Supramolecular ring-versus-chain equilibria are ubiquitous in biological and synthetic systems. Understanding the factors that decide whether a system will fall on one side or the other is crucial to the control of molecular self-assembly. This work reports results with two kinds of dinucleoside monomers, in which the balance between closed cycles and open polymers is found to depend on subtle factors that rule conformational equilibria, such as steric hindrance, intramolecular interactions, or π-conjugation pathways.

Original languageEnglish
Pages (from-to)11983-11991
Number of pages9
JournalChemistry - A European Journal
Volume24
Issue number46
Early online date9 May 2018
DOIs
Publication statusPublished - 14 Aug 2018

Bibliographical note

Special Issue: 7th EuCheMS Chemistry Congress, Liverpool

Funding

Funding from the European Research Council (ERC-StG 279548) and MINECO (CTQ2014-27729-P and CTQ2017-84727-P) is gratefully acknowledged (D.G.R.). C.F.G. gratefully acknowledges financial support from the Netherlands Organization for Scientific Research NWO (ECHO).

FundersFunder number
Netherlands Organization for Scientific Research NWO
Seventh Framework Programme279548
European Research Council
Ministerio de Economía y CompetitividadCTQ2017-84727-P, CTQ2014-27729-P

    Keywords

    • chelates
    • conformational effects
    • self-assembly
    • supramolecular chemistry

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