Impact of nutrition on muscle mass, strength, and performance in older adults

A. Mithal, J.P. Bonjour, S. Boonen, P. Burckhardt, H. Degens, G.E. Fuleihan, R. Josse, P.T.A.M. Lips, J.M. Torres, R. Rizzoli, N. Yoshimura, D.A. Wahl, C. Cooper, B. Dawson-Hughes

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Muscle strength plays an important role in determining risk for falls, which result in fractures and other injuries. While bone loss has long been recognized as an inevitable consequence of aging, sarcopenia - the gradual loss of skeletal muscle mass and strength that occurs with advancing age - has recently received increased attention. A review of the literature was undertaken to identify nutritional factors that contribute to loss of muscle mass. The role of protein, acid-base balance, vitamin D/calcium, and other minor nutrients like B vitamins was reviewed. Muscle wasting is a multifactorial process involving intrinsic and extrinsic alterations. A loss of fast twitch fibers, glycation of proteins, and insulin resistance may play an important role in the loss of muscle strength and development of sarcopenia. Protein intake plays an integral part in muscle health and an intake of 1.0-1.2 g/kg of body weight per day is probably optimal for older adults. There is a moderate inverse relationship between vitamin D status and muscle strength. Chronic ingestion of acid-producing diets appears to have a negative impact on muscle performance, and decreases in vitamin B
    Original languageEnglish
    Pages (from-to)1555-1566
    JournalOsteoporosis International
    Volume24
    Issue number5
    DOIs
    Publication statusPublished - 2013

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