Impacts of Different Exposure Scenarios on Transcript Abundances in Danio rerio Embryos when Investigating the Toxicological Burden of Riverine Sediments.

K. Bluhm; J Otte; L. Yang; C. Zinsmeister; J.B. Legradi; S. Keiter; T. Kosmehl; T. Braunbeck; U. Straehle; H. Hollert

doi:10.1371/journal.pone.0106523

Impacts of Different Exposure Scenarios on Transcript Abundances in Danio rerio Embryos when Investigating the Toxicological Burden of Riverine Sediments.

K. Bluhm, J Otte, L. Yang, C. Zinsmeister, J.B. Legradi, S. Keiter, T. Kosmehl, T. Braunbeck, U. Straehle, H. Hollert

Chemistry and Biology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Purpose: Recently, a proof-of-concept study revealed the suitability of transcriptome analyses to obtain and assess changes in the abundance of transcripts in zebrafish (Danio rerio) embryos after exposure to organic sediment extracts. The present study investigated changes in the transcript abundance in zebrafish embryos exposed to whole sediment samples and corresponding organic extracts in order to identify the impact of different exposure pathways on sediment toxicity.

Original language	English
Pages (from-to)	e106523
Journal	PLoS ONE
Volume	9
Issue number	9
DOIs	https://doi.org/10.1371/journal.pone.0106523
Publication status	Published - 2014

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title = "Impacts of Different Exposure Scenarios on Transcript Abundances in Danio rerio Embryos when Investigating the Toxicological Burden of Riverine Sediments.",

abstract = "Purpose: Recently, a proof-of-concept study revealed the suitability of transcriptome analyses to obtain and assess changes in the abundance of transcripts in zebrafish (Danio rerio) embryos after exposure to organic sediment extracts. The present study investigated changes in the transcript abundance in zebrafish embryos exposed to whole sediment samples and corresponding organic extracts in order to identify the impact of different exposure pathways on sediment toxicity.",

author = "K. Bluhm and J Otte and L. Yang and C. Zinsmeister and J.B. Legradi and S. Keiter and T. Kosmehl and T. Braunbeck and U. Straehle and H. Hollert",

year = "2014",

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AU - Bluhm, K.

AU - Otte, J

AU - Yang, L.

AU - Zinsmeister, C.

AU - Legradi, J.B.

AU - Keiter, S.

AU - Kosmehl, T.

AU - Braunbeck, T.

AU - Straehle, U.

AU - Hollert, H.

PY - 2014

Y1 - 2014

N2 - Purpose: Recently, a proof-of-concept study revealed the suitability of transcriptome analyses to obtain and assess changes in the abundance of transcripts in zebrafish (Danio rerio) embryos after exposure to organic sediment extracts. The present study investigated changes in the transcript abundance in zebrafish embryos exposed to whole sediment samples and corresponding organic extracts in order to identify the impact of different exposure pathways on sediment toxicity.

AB - Purpose: Recently, a proof-of-concept study revealed the suitability of transcriptome analyses to obtain and assess changes in the abundance of transcripts in zebrafish (Danio rerio) embryos after exposure to organic sediment extracts. The present study investigated changes in the transcript abundance in zebrafish embryos exposed to whole sediment samples and corresponding organic extracts in order to identify the impact of different exposure pathways on sediment toxicity.

U2 - 10.1371/journal.pone.0106523

DO - 10.1371/journal.pone.0106523

M3 - Article

SN - 1932-6203

VL - 9

SP - e106523

JO - PLoS ONE

JF - PLoS ONE

IS - 9

ER -

Impacts of Different Exposure Scenarios on Transcript Abundances in Danio rerio Embryos when Investigating the Toxicological Burden of Riverine Sediments.

Abstract

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