Implant supported overdentures in Sjögren's disease patients: a multicentre prospective cohort study

Floor Maarse, Willem M.M. Fennis, Jos W.R. Twisk, Anke Korfage, Hendrik J. Santing, Laurens den Hartog, Marvick S.M. Muradin, Gerry M. Raghoebar, Arjan Vissink, Henk S. Brand, Derk Hendrik Jan Jager

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

OBJECTIVES: To prospectively investigate patient-reported outcomes and clinical performance of implant supported overdentures in edentulous Sjögren's disease (SjD) patients compared to subjects without SjD. METHODS: 51 implants were placed in 12 patients with SjD and 50 implants in 12 non-SjD patients to support overdentures. Clinical performance, marginal bone-level changes, patient satisfaction and oral health related quality of life (OHRQoL) were assessed at 1 (T1), 6 (T6), 12 (T12) and 18 (T18) months after placement of the overdenture. Patient satisfaction, ability to chew and OHRQoL were assessed with validated questionnaires. Marginal bone-level changes were measured on standardised dental radiographs. Clinical parameters included implant and overdenture survival, plaque, bleeding and gingival indices, and probing depth. RESULTS: OHRQoL in patients with SjD improved significantly after placement of implant supported overdentures at all measuring moments compared to baseline (p<0.05). Nevertheless, ability to chew tough and hard food was significantly better for non-SjD patients at all timepoints after placement of an implant supported overdenture (p<0.05). Implant survival at T18 was 100% in the patients with SjD and 98% in the non-SS group. Mean marginal bone loss at T18 did not differ between patients with SjD and non-SS patients, 1.12±0.74 mm and 1.43±1.66 mm, respectively (p=0.58). Clinical performance was good with no differences between the groups for all outcome measures (p>0.05). CONCLUSIONS: Implant-supported overdentures have a positive effect on OHRQoL and dental implants can be successfully applied in edentulous patients with SjD with nearly similar outcomes as in non-SjD subjects.

Original languageEnglish
Pages (from-to)2418-2427
Number of pages10
JournalClinical and Experimental Rheumatology
Volume41
Issue number12
Early online date23 Dec 2023
DOIs
Publication statusPublished - Dec 2023

Funding

Funding: this study was funded by unconditional research grants from Foundation NutsOhra (FNO; grant/award number: 1303-042), Amsterdam, the Netherlands and Biohorizons Inc (grant/award number: CI15002), Birmingham, AL, USA. Competing interests: none declared.

FundersFunder number
Netherlands and Biohorizons IncCI15002
Fonds NutsOhra1303-042

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