Implantation of resorbable gentamicin sponges in addition to irrigation and debridement in 34 patients with infection complicating total hip arthroplasty

Jesse W.P. Kuiper, Richard M. Brohet, Sander Wassink, Michel P.J. Van den Bekerom, Petrus A. Nolte, Diederik A. Vergroesen

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

We evaluated a prosthesis-retaining treatment protocol for prosthetic joint infection in patients presenting at a mean of 116 days (range 10-1216 days) after primary arthroplasty. Our regime involved irrigation and debridement followed by implantation of biodegradable gentamicin loaded sponges which do not require removal after implantation. Of 34 patients with a deep infection after total hip arthroplasty, Twenty-five were treated successfully, with a mean follow-up of 35 months. There were no permanent complications. This success rate is comparable to earlier studies. Early initiation of treatment demonstrated a tendency for better results, and late chronic infections had a worse outcome. Because the sponges are degradable, a number of further surgical procedures were avoided.

Original languageEnglish
Pages (from-to)173-180
Number of pages8
JournalHip International
Volume23
Issue number2
DOIs
Publication statusPublished - 1 Mar 2013
Externally publishedYes

Keywords

  • Arthroplasty
  • Debridement
  • Gentamicin
  • Hip
  • Infection
  • Sponges

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