Implementation of a combined association-linkage model for quantitative traits in linear mixed model procedures of statistical packages

A.L. Beem; D.I. Boomsma

doi:10.1375/183242706777591272

Implementation of a combined association-linkage model for quantitative traits in linear mixed model procedures of statistical packages

A.L. Beem, D.I. Boomsma

Biological Psychology

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Abstract

A transmission disequilibrium test for quantitative traits which combines association and linkage analyses is currently available in several dedicated software packages. We describe how to implement such models in linear mixed model procedures that are available in widely used statistical packages such as SPSS. We also briefly mention a few extensions of the model that become naturally available once the model is implemented in such procedures.

Original language	English
Pages (from-to)	325-333
Journal	Twin Research and Human Genetics
Volume	9
Issue number	3
DOIs	https://doi.org/10.1375/183242706777591272
Publication status	Published - 2006

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Netherlands Twin Register (NTR)

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10.1375/183242706777591272

Beem Twin Research and Human Genetics 9(3) 2006 uFinal published version, 129 KB

http://www.tweelingenregister.org/nederlands/verslaggeving/NTR_publicaties_2006/Beem_TRHG_2006.pdf

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Implementation of a combined association-linkage model for quantitative traits in linear mixed model procedures of statistical packages

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