In vitro and cellular systems for the characterization of bioactivating and inactivating drug metabolizing enzymes in adverse drug reactions: Insights into amodiaquine idiosyncratic toxicity

Y. Zhang

Research output: PhD ThesisPhD Thesis - Research VU Amsterdam, graduation VU Amsterdam

251 Downloads (Pure)
Original languageEnglish
QualificationPhD
Awarding Institution
  • Vrije Universiteit Amsterdam
Supervisors/Advisors
  • Vermeulen, Nico P.E., Supervisor
  • Commandeur, Jan, Co-supervisor
Award date5 Feb 2018
Publication statusPublished - 2018

Keywords

  • adverse drug reaction; drug metabolizing enzymes; reactive drug metabolites; amodiaquine; toxicity

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