In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

H. Sudkamp; P. Koch; H. Spahr; D. Hillmann; G. Franke; M. Münst; F. Reinholz; R. Birngruber; G. Hüttmann

doi:10.1364/OL.41.004987

In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

H. Sudkamp, P. Koch, H. Spahr, D. Hillmann, G. Franke, M. Münst, F. Reinholz, R. Birngruber, G. Hüttmann

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

© 2016 Optical Society of America.With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices.

Original language	English
Pages (from-to)	4987-4990
Journal	Optics Letters
Volume	41
Issue number	21
DOIs	https://doi.org/10.1364/OL.41.004987
Publication status	Published - 1 Nov 2016
Externally published	Yes

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abstract = "{\textcopyright} 2016 Optical Society of America.With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices.",

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AU - Sudkamp, H.

AU - Koch, P.

AU - Spahr, H.

AU - Hillmann, D.

AU - Franke, G.

AU - Münst, M.

AU - Reinholz, F.

AU - Birngruber, R.

AU - Hüttmann, G.

PY - 2016/11/1

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AB - © 2016 Optical Society of America.With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices.

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EP - 4990

JO - Optics Letters

JF - Optics Letters

IS - 21

ER -

In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

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