Increase in bone mineral density in strictly treated Crohn's disease patients with concomitant calcium and vitamin D supplementation

S.F. Bakker, V.K. Dik, B.I. Witte, P.T.A.M. Lips, J.C. Roos, A.A. van Bodegraven

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Background and aims: Decreased bone mineral density (BMD) is common in Crohn's disease (CD) patients. This paper reports on the prevalence of decreased BMD in a referral cohort study of CD-patients next to the change of BMD over time in relation with CD-associated clinical characteristics. Methods: 205 CD patients of a referral hospital were enrolled between januari 1998-January 2010 when measurement of BMD by dual X-ray absorptiometry (DXA) was available. Follow-up DXA scan was performed in subjects with known risk factors besides Crohn indicative for low BMD. Treatment of CD patients was according to a protocol which is comparable to the current (inter)national guidelines. In osteopenic patients, supplemental vitamin D (800. IU) and Calcium (500-1000. mg) were prescribed. Results: Mean BMD at baseline was 0.97±0.16gram/cm
    Original languageEnglish
    Pages (from-to)377-384
    JournalJournal of Crohn's and Colitis
    Volume7
    Issue number5
    DOIs
    Publication statusPublished - 2013

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