Injury markers predict time to dementia in subjects with MCI and amyloid pathology

I.A. van Rossum, S.J.B. Vos, L. Burns, D.L. Knol, P. Scheltens, H. Soininen, L.O. Wahlund, H. Hampel, M. Tsolaki, L. Minthon, G. L'Italien, W.M. van der Flier, C.E. Teunissen, K. Blennow, F. Barkhof, D. Rueckert, R. Wolz, F. Verhey, P.J. Visser

    Research output: Contribution to JournalArticleAcademicpeer-review

    139 Downloads (Pure)


    Objectives: Alzheimer disease (AD) can now be diagnosed in subjects with mild cognitive impairment (MCI) using biomarkers. However, little is known about the rate of decline in those subjects. In this cohort study, we aimed to assess the conversion rate to dementia and identify prognostic markers in subjects with MCI and evidence of amyloid pathology. Methods: We pooled subjects from the VU University Medical Center Alzheimer Center and the Development of Screening Guidelines and Criteria for Predementia Alzheimer's Disease (DESCRIPA) study. We included subjects with MCI, an abnormal level of β-amyloid
    Original languageEnglish
    Pages (from-to)1809-1816
    Issue number17
    Publication statusPublished - 2012


    Dive into the research topics of 'Injury markers predict time to dementia in subjects with MCI and amyloid pathology'. Together they form a unique fingerprint.

    Cite this