Inter-individual variation in hepatic drug metabolism: The potential of in vitro assays in unraveling the role of metabolism in drug induced liver toxicity

S.P. den Braver-Sewradj

Inter-individual variation in hepatic drug metabolism: The potential of in vitro assays in unraveling the role of metabolism in drug induced liver toxicity

S.P. den Braver-Sewradj

Research output: PhD Thesis › PhD-Thesis - Research and graduation internal

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Original language	English
Qualification	PhD
Awarding Institution	Vrije Universiteit Amsterdam
Supervisors/Advisors	Vermeulen, Nico P.E., Supervisor Commandeur, J.N.M., Co-supervisor Vos, JC, Co-supervisor
Award date	20 Feb 2018
Print ISBNs	9789462958357, 9462958351
Publication status	Published - 2018

Keywords

drug metabolism; drug induced liver injury; hepatotoxicity; in vitro assays; inter-individual variability; idiosyncratic

Access to Document

CoverFinal published version, 5.7 MB
Title pageFinal published version, 150 KB
Abstract dutchFinal published version, 225 KB
Abstract englishFinal published version, 343 KB
Table of contentsFinal published version, 103 KB
Complete dissertationFinal published version, 8.61 MB

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Cite this

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title = "Inter-individual variation in hepatic drug metabolism: The potential of in vitro assays in unraveling the role of metabolism in drug induced liver toxicity",

keywords = "drug metabolism; drug induced liver injury; hepatotoxicity; in vitro assays; inter-individual variability; idiosyncratic",

author = "{den Braver-Sewradj}, S.P.",

year = "2018",

language = "English",

isbn = "9789462958357",

school = "Vrije Universiteit Amsterdam",

}

TY - THES

T1 - Inter-individual variation in hepatic drug metabolism

T2 - The potential of in vitro assays in unraveling the role of metabolism in drug induced liver toxicity

AU - den Braver-Sewradj, S.P.

PY - 2018

Y1 - 2018

KW - drug metabolism; drug induced liver injury; hepatotoxicity; in vitro assays; inter-individual variability; idiosyncratic

M3 - PhD-Thesis - Research and graduation internal

SN - 9789462958357

SN - 9462958351

ER -