Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts

Susan Branje; Sanne Geeraerts; Eveline L. de Zeeuw; Anoek M. Oerlemans; M. Elisabeth Koopman-Verhoeff; Susanne Schulz; Stefanie Nelemans; Wim Meeus; Catharina A. Hartman; Manon H.J. Hillegers; Albertine J. Oldehinkel; Dorret I. Boomsma

doi:10.1016/j.dcn.2020.100835

Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts

Susan Branje^*, Sanne Geeraerts, Eveline L. de Zeeuw, Anoek M. Oerlemans, M. Elisabeth Koopman-Verhoeff, Susanne Schulz, Stefanie Nelemans, Wim Meeus, Catharina A. Hartman, Manon H.J. Hillegers, Albertine J. Oldehinkel, Dorret I. Boomsma

^*Corresponding author for this work

Research output: Contribution to Journal › Review article › Academic › peer-review

Abstract

Behaviors, traits and characteristics are transmitted from parents to offspring because of complex genetic and non-genetic processes. We review genetic and non-genetic mechanisms of intergenerational transmission of psychopathology and parenting and focus on recent methodological advances in disentangling genetic and non-genetic factors. In light of this review, we propose that future studies on intergenerational transmission should aim to disentangle genetic and non-genetic transmission, take a long-term longitudinal perspective, and focus on paternal and maternal intergenerational transmission. We present four large longitudinal cohort studies within the Consortium on Individual Development, which together address many of these methodological challenges. These four cohort studies aim to examine the extent to which genetic and non-genetic transmission from the parental generation shapes parenting behavior and psychopathology in the next generation, as well as the extent to which self-regulation and social competence mediate this transmission. Conjointly, these four cohorts provide a comprehensive approach to the study of intergenerational transmission.

Original language	English
Article number	100835
Pages (from-to)	1-12
Number of pages	12
Journal	Developmental Cognitive Neuroscience
Volume	45
Early online date	8 Aug 2020
DOIs	https://doi.org/10.1016/j.dcn.2020.100835
Publication status	Published - Oct 2020

Funding

This work was supported by the Netherlands Organization for Scientific Research (NWO; grant number 024.001.003 ); NWO Groot ( 480-15-001/674 ): Netherlands Twin Registry Repository: researching the interplay between genome and environment and an innovative ideas grant of the European Research Council (ERC CoG INTRANSITION 773023 to SB).

Funders	Funder number
Netherlands Organization for Scientific Research
Horizon 2020 Framework Programme	773023
European Research Council
Nederlandse Organisatie voor Wetenschappelijk Onderzoek	024.001.003, 480-15-001/674

Keywords

Children
Gene-environment
Intergenerational transmission
Longitudinal
Parent

Cohort Studies

Netherlands Twin Register (NTR)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.dcn.2020.100835

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Branje, S., Geeraerts, S., de Zeeuw, E. L., Oerlemans, A. M., Koopman-Verhoeff, M. E., Schulz, S., Nelemans, S., Meeus, W., Hartman, C. A., Hillegers, M. H. J., Oldehinkel, A. J., & Boomsma, D. I. (2020). Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts. Developmental Cognitive Neuroscience, 45, 1-12. Article 100835. https://doi.org/10.1016/j.dcn.2020.100835

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title = "Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts",

abstract = "Behaviors, traits and characteristics are transmitted from parents to offspring because of complex genetic and non-genetic processes. We review genetic and non-genetic mechanisms of intergenerational transmission of psychopathology and parenting and focus on recent methodological advances in disentangling genetic and non-genetic factors. In light of this review, we propose that future studies on intergenerational transmission should aim to disentangle genetic and non-genetic transmission, take a long-term longitudinal perspective, and focus on paternal and maternal intergenerational transmission. We present four large longitudinal cohort studies within the Consortium on Individual Development, which together address many of these methodological challenges. These four cohort studies aim to examine the extent to which genetic and non-genetic transmission from the parental generation shapes parenting behavior and psychopathology in the next generation, as well as the extent to which self-regulation and social competence mediate this transmission. Conjointly, these four cohorts provide a comprehensive approach to the study of intergenerational transmission.",

keywords = "Children, Gene-environment, Intergenerational transmission, Longitudinal, Parent",

author = "Susan Branje and Sanne Geeraerts and {de Zeeuw}, {Eveline L.} and Oerlemans, {Anoek M.} and Koopman-Verhoeff, {M. Elisabeth} and Susanne Schulz and Stefanie Nelemans and Wim Meeus and Hartman, {Catharina A.} and Hillegers, {Manon H.J.} and Oldehinkel, {Albertine J.} and Boomsma, {Dorret I.}",

year = "2020",

month = oct,

doi = "10.1016/j.dcn.2020.100835",

language = "English",

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Branje, S, Geeraerts, S, de Zeeuw, EL, Oerlemans, AM, Koopman-Verhoeff, ME, Schulz, S, Nelemans, S, Meeus, W, Hartman, CA, Hillegers, MHJ, Oldehinkel, AJ & Boomsma, DI 2020, 'Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts', Developmental Cognitive Neuroscience, vol. 45, 100835, pp. 1-12. https://doi.org/10.1016/j.dcn.2020.100835

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T2 - Theoretical and methodological issues and an introduction to four Dutch cohorts

AU - Branje, Susan

AU - Geeraerts, Sanne

AU - de Zeeuw, Eveline L.

AU - Oerlemans, Anoek M.

AU - Koopman-Verhoeff, M. Elisabeth

AU - Schulz, Susanne

AU - Nelemans, Stefanie

AU - Meeus, Wim

AU - Hartman, Catharina A.

AU - Hillegers, Manon H.J.

AU - Oldehinkel, Albertine J.

AU - Boomsma, Dorret I.

PY - 2020/10

Y1 - 2020/10

N2 - Behaviors, traits and characteristics are transmitted from parents to offspring because of complex genetic and non-genetic processes. We review genetic and non-genetic mechanisms of intergenerational transmission of psychopathology and parenting and focus on recent methodological advances in disentangling genetic and non-genetic factors. In light of this review, we propose that future studies on intergenerational transmission should aim to disentangle genetic and non-genetic transmission, take a long-term longitudinal perspective, and focus on paternal and maternal intergenerational transmission. We present four large longitudinal cohort studies within the Consortium on Individual Development, which together address many of these methodological challenges. These four cohort studies aim to examine the extent to which genetic and non-genetic transmission from the parental generation shapes parenting behavior and psychopathology in the next generation, as well as the extent to which self-regulation and social competence mediate this transmission. Conjointly, these four cohorts provide a comprehensive approach to the study of intergenerational transmission.

AB - Behaviors, traits and characteristics are transmitted from parents to offspring because of complex genetic and non-genetic processes. We review genetic and non-genetic mechanisms of intergenerational transmission of psychopathology and parenting and focus on recent methodological advances in disentangling genetic and non-genetic factors. In light of this review, we propose that future studies on intergenerational transmission should aim to disentangle genetic and non-genetic transmission, take a long-term longitudinal perspective, and focus on paternal and maternal intergenerational transmission. We present four large longitudinal cohort studies within the Consortium on Individual Development, which together address many of these methodological challenges. These four cohort studies aim to examine the extent to which genetic and non-genetic transmission from the parental generation shapes parenting behavior and psychopathology in the next generation, as well as the extent to which self-regulation and social competence mediate this transmission. Conjointly, these four cohorts provide a comprehensive approach to the study of intergenerational transmission.

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KW - Gene-environment

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Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts

Abstract

Funding

Keywords

Cohort Studies

UN SDGs

Access to Document

Persistent URL (handle)

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