Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors.

M.J. Smit; R. Leurs; A.E. Alewijnse; J. Blauw; G.P. van Nieuw Amerongen; Y. van de Vrede; E. Roovers; H. Timmerman

doi:10.1073/pnas.93.13.6802

Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors.

M.J. Smit
, R. Leurs
, A.E. Alewijnse
, J. Blauw
, G.P. van Nieuw Amerongen
, Y. van de Vrede
, E. Roovers
, H. Timmerman

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Histamine H

Original language	English
Pages (from-to)	6802-9807
Journal	Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Volume	93
DOIs	https://doi.org/10.1073/pnas.93.13.6802
Publication status	Published - 1996

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SDG 3 Good Health and Well-being

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10.1073/pnas.93.13.6802

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Smit, M. J., Leurs, R., Alewijnse, A. E., Blauw, J., van Nieuw Amerongen, G. P., van de Vrede, Y., Roovers, E., & Timmerman, H. (1996). Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 93, 6802-9807. https://doi.org/10.1073/pnas.93.13.6802

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title = "Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors.",

abstract = "Histamine H",

author = "M.J. Smit and R. Leurs and A.E. Alewijnse and J. Blauw and \{van Nieuw Amerongen\}, G.P. and \{van de Vrede\}, Y. and E. Roovers and H. Timmerman",

year = "1996",

doi = "10.1073/pnas.93.13.6802",

language = "English",

volume = "93",

pages = "6802--9807",

journal = "Proceedings of the National Academy of Sciences of the United States of America (PNAS)",

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Smit, MJ , Leurs, R, Alewijnse, AE, Blauw, J, van Nieuw Amerongen, GP, van de Vrede, Y, Roovers, E & Timmerman, H 1996, 'Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors.', Proceedings of the National Academy of Sciences of the United States of America (PNAS), vol. 93, pp. 6802-9807. https://doi.org/10.1073/pnas.93.13.6802

TY - JOUR

T1 - Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors.

AU - Smit, M.J.

AU - Leurs, R.

AU - Alewijnse, A.E.

AU - Blauw, J.

AU - van Nieuw Amerongen, G.P.

AU - van de Vrede, Y.

AU - Roovers, E.

AU - Timmerman, H.

PY - 1996

Y1 - 1996

N2 - Histamine H

AB - Histamine H

U2 - 10.1073/pnas.93.13.6802

DO - 10.1073/pnas.93.13.6802

M3 - Article

SN - 0027-8424

VL - 93

SP - 6802

EP - 9807

JO - Proceedings of the National Academy of Sciences of the United States of America (PNAS)

JF - Proceedings of the National Academy of Sciences of the United States of America (PNAS)

ER -

Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active histamine H2 receptors.

Abstract

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