Invigorating discovery and clinical translation of aging biomarkers

Erik Jacques; Chiara Herzog; Kejun Ying; Alan Tomusiak; Jessica Kasamoto; Raghav Sehgal; Seth Paulson; Julian Reinhard; Jakob Träuble; Waylon J. Hastings; Alexander Tyshkovskiy; Sara Hägg; John C. Earls; Christian E. Behrens; Jessica Lasky-Su; Gavin Zhou; Eric Morgen; John S. Tsang; Riccardo E. Marioni; Xiao Jun Ma; Alexandra Stolzing; Christin Glorioso; Jonathan S. Gootenberg; Omar O. Abudayyeh; M. Austin Argentieri; Raymond H. Mak; Lynne S. Cox; Andrew S. Brack; Gordan Lauc; David Furman; Jason D. Buenrostro; Björn Schumacher; Jamie N. Justice; Tina Woods; David Gobel; Viviana I. Perez; David A. Sinclair; Andrea B. Maier; Nir Barzilai; Michael P. Snyder; Tony Wyss-Coray; Steve Horvath; Luigi Ferrucci; Jesse R. Poganik; Mahdi Moqri; Vadim N. Gladyshev

doi:10.1038/s43587-025-00838-w

Invigorating discovery and clinical translation of aging biomarkers

Erik Jacques, Chiara Herzog, Kejun Ying, Alan Tomusiak, Jessica Kasamoto, Raghav Sehgal, Seth Paulson, Julian Reinhard, Jakob Träuble, Waylon J. Hastings, Alexander Tyshkovskiy, Sara Hägg, John C. Earls, Christian E. Behrens, Jessica Lasky-Su, Gavin Zhou, Eric Morgen, John S. Tsang, Riccardo E. Marioni, Xiao Jun MaAlexandra Stolzing, Christin Glorioso, Jonathan S. Gootenberg, Omar O. Abudayyeh, M. Austin Argentieri, Raymond H. Mak, Lynne S. Cox, Andrew S. Brack, Gordan Lauc, David Furman, Jason D. Buenrostro, Björn Schumacher, Jamie N. Justice, Tina Woods, David Gobel, Viviana I. Perez, David A. Sinclair, Andrea B. Maier, Nir Barzilai, Michael P. Snyder, Tony Wyss-Coray, Steve Horvath, Luigi Ferrucci, Jesse R. Poganik^*, Mahdi Moqri^*, Vadim N. Gladyshev^*

^*Corresponding author for this work

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

On 1–2 November 2024, the annual Biomarkers of Aging conference welcomed academic and industry scientists, and partners from governmental and nongovernmental organizations, to Harvard Medical School in Boston, USA, to discuss new insights into measuring and monitoring human aging, with the aim of clinical translation. In this Meeting Report, we summarize the conference and offer potential future directions for the Biomarkers of Aging Consortium and the longevity science community at large.

Original language	English
Pages (from-to)	539-543
Number of pages	5
Journal	Nature Aging
Volume	5
Issue number	4
Early online date	31 Mar 2025
DOIs	https://doi.org/10.1038/s43587-025-00838-w
Publication status	Published - Apr 2025

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Publisher Copyright:
© Springer Nature America, Inc. 2025.

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Jacques, E., Herzog, C., Ying, K., Tomusiak, A., Kasamoto, J., Sehgal, R., Paulson, S., Reinhard, J., Träuble, J., Hastings, W. J., Tyshkovskiy, A., Hägg, S., Earls, J. C., Behrens, C. E., Lasky-Su, J., Zhou, G., Morgen, E., Tsang, J. S., Marioni, R. E., ... Gladyshev, V. N. (2025). Invigorating discovery and clinical translation of aging biomarkers. Nature Aging, 5(4), 539-543. https://doi.org/10.1038/s43587-025-00838-w

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title = "Invigorating discovery and clinical translation of aging biomarkers",

abstract = "On 1–2 November 2024, the annual Biomarkers of Aging conference welcomed academic and industry scientists, and partners from governmental and nongovernmental organizations, to Harvard Medical School in Boston, USA, to discuss new insights into measuring and monitoring human aging, with the aim of clinical translation. In this Meeting Report, we summarize the conference and offer potential future directions for the Biomarkers of Aging Consortium and the longevity science community at large.",

author = "Erik Jacques and Chiara Herzog and Kejun Ying and Alan Tomusiak and Jessica Kasamoto and Raghav Sehgal and Seth Paulson and Julian Reinhard and Jakob Tr{\"a}uble and Hastings, \{Waylon J.\} and Alexander Tyshkovskiy and Sara H{\"a}gg and Earls, \{John C.\} and Behrens, \{Christian E.\} and Jessica Lasky-Su and Gavin Zhou and Eric Morgen and Tsang, \{John S.\} and Marioni, \{Riccardo E.\} and Ma, \{Xiao Jun\} and Alexandra Stolzing and Christin Glorioso and Gootenberg, \{Jonathan S.\} and Abudayyeh, \{Omar O.\} and Argentieri, \{M. Austin\} and Mak, \{Raymond H.\} and Cox, \{Lynne S.\} and Brack, \{Andrew S.\} and Gordan Lauc and David Furman and Buenrostro, \{Jason D.\} and Bj{\"o}rn Schumacher and Justice, \{Jamie N.\} and Tina Woods and David Gobel and Perez, \{Viviana I.\} and Sinclair, \{David A.\} and Maier, \{Andrea B.\} and Nir Barzilai and Snyder, \{Michael P.\} and Tony Wyss-Coray and Steve Horvath and Luigi Ferrucci and Poganik, \{Jesse R.\} and Mahdi Moqri and Gladyshev, \{Vadim N.\}",

note = "Publisher Copyright: {\textcopyright} Springer Nature America, Inc. 2025.",

year = "2025",

month = apr,

doi = "10.1038/s43587-025-00838-w",

language = "English",

volume = "5",

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Jacques, E, Herzog, C, Ying, K, Tomusiak, A, Kasamoto, J, Sehgal, R, Paulson, S, Reinhard, J, Träuble, J, Hastings, WJ, Tyshkovskiy, A, Hägg, S, Earls, JC, Behrens, CE, Lasky-Su, J, Zhou, G, Morgen, E, Tsang, JS, Marioni, RE, Ma, XJ, Stolzing, A, Glorioso, C, Gootenberg, JS, Abudayyeh, OO, Argentieri, MA, Mak, RH, Cox, LS, Brack, AS, Lauc, G, Furman, D, Buenrostro, JD, Schumacher, B, Justice, JN, Woods, T, Gobel, D, Perez, VI, Sinclair, DA, Maier, AB, Barzilai, N, Snyder, MP, Wyss-Coray, T, Horvath, S, Ferrucci, L, Poganik, JR, Moqri, M & Gladyshev, VN 2025, 'Invigorating discovery and clinical translation of aging biomarkers', Nature Aging, vol. 5, no. 4, pp. 539-543. https://doi.org/10.1038/s43587-025-00838-w

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AU - Paulson, Seth

AU - Reinhard, Julian

AU - Träuble, Jakob

AU - Hastings, Waylon J.

AU - Tyshkovskiy, Alexander

AU - Hägg, Sara

AU - Earls, John C.

AU - Behrens, Christian E.

AU - Lasky-Su, Jessica

AU - Zhou, Gavin

AU - Morgen, Eric

AU - Tsang, John S.

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AU - Stolzing, Alexandra

AU - Glorioso, Christin

AU - Gootenberg, Jonathan S.

AU - Abudayyeh, Omar O.

AU - Argentieri, M. Austin

AU - Mak, Raymond H.

AU - Cox, Lynne S.

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AU - Furman, David

AU - Buenrostro, Jason D.

AU - Schumacher, Björn

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AU - Gobel, David

AU - Perez, Viviana I.

AU - Sinclair, David A.

AU - Maier, Andrea B.

AU - Barzilai, Nir

AU - Snyder, Michael P.

AU - Wyss-Coray, Tony

AU - Horvath, Steve

AU - Ferrucci, Luigi

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VL - 5

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JO - Nature Aging

JF - Nature Aging

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ER -

Invigorating discovery and clinical translation of aging biomarkers

Abstract

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