Is the introduction of more advanced radiotherapy techniques for locally-advanced head and neck cancer associated with improved quality of life and reduced symptom burden?

Max Dahele; Jim P. Tol; Marije R. Vergeer; Femke Jansen; Birgit I. Lissenberg-Witte; C. Rene Leemans; Ben J. Slotman; Irma M. Verdonck-de Leeuw; Wilko F.A.R. Verbakel

doi:10.1016/j.radonc.2020.08.026

Is the introduction of more advanced radiotherapy techniques for locally-advanced head and neck cancer associated with improved quality of life and reduced symptom burden?

Max Dahele, Jim P. Tol, Marije R. Vergeer, Femke Jansen, Birgit I. Lissenberg-Witte, C. Rene Leemans, Ben J. Slotman, Irma M. Verdonck-de Leeuw, Wilko F.A.R. Verbakel^*

^*Corresponding author for this work

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Technical improvements in head and neck cancer radiotherapy over the last decade have resulted in substantial reductions in dose to organs-at-risk. For a mix of tumors, we saw less xerostomia moving from 3D-conformal to more advanced techniques. For oropharynx-only there were additional improvements, including in global quality-of-life and sticky saliva.

Original language	English
Pages (from-to)	298-303
Number of pages	6
Journal	Radiotherapy and Oncology
Volume	151
DOIs	https://doi.org/10.1016/j.radonc.2020.08.026
Publication status	Published - Oct 2020

Funding

Verdonck-de Leeuw received research grants from the Dutch Cancer Society, Alpe d’HuZes Foundation, Netherlands Organization for Health Research and Development (ZonMW), Pink Ribbon, SAG Foundation, Zilveren Kruis health care insurance company, CZ health care insurance company, Danone Ecofund, Nutricia, Dutch Society Head and Neck Cancer Patients, Michel Keijzer Foundation, Red-kite distributor of eHealth tools, and Bristol Meyers Squibb, all outside the submitted work.

Funders	Funder number
Alpe d’HuZes Foundation
Danone Ecofund, Nutricia, Dutch Society Head and Neck Cancer Patients
Dutch Cancer Society
Michel Keijzer Foundation
Netherlands Organization for Health Research and Development
SAG Foundation
Bristol-Myers Squibb
ZonMw

Keywords

Head and neck radiotherapy
Organ at risk sparing
Patient reported outcome
Quality of life

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.radonc.2020.08.026

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Cite this

Dahele, M., Tol, J. P., Vergeer, M. R., Jansen, F., Lissenberg-Witte, B. I., Leemans, C. R., Slotman, B. J., Verdonck-de Leeuw, I. M., & Verbakel, W. F. A. R. (2020). Is the introduction of more advanced radiotherapy techniques for locally-advanced head and neck cancer associated with improved quality of life and reduced symptom burden? Radiotherapy and Oncology, 151, 298-303. https://doi.org/10.1016/j.radonc.2020.08.026

@article{af4106fbb1034054a6e195bfc1d87606,

title = "Is the introduction of more advanced radiotherapy techniques for locally-advanced head and neck cancer associated with improved quality of life and reduced symptom burden?",

abstract = "Technical improvements in head and neck cancer radiotherapy over the last decade have resulted in substantial reductions in dose to organs-at-risk. For a mix of tumors, we saw less xerostomia moving from 3D-conformal to more advanced techniques. For oropharynx-only there were additional improvements, including in global quality-of-life and sticky saliva.",

keywords = "Head and neck radiotherapy, Organ at risk sparing, Patient reported outcome, Quality of life",

author = "Max Dahele and Tol, {Jim P.} and Vergeer, {Marije R.} and Femke Jansen and Lissenberg-Witte, {Birgit I.} and Leemans, {C. Rene} and Slotman, {Ben J.} and {Verdonck-de Leeuw}, {Irma M.} and Verbakel, {Wilko F.A.R.}",

year = "2020",

month = oct,

doi = "10.1016/j.radonc.2020.08.026",

language = "English",

volume = "151",

pages = "298--303",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",