Molecular medicine is undergoing a revolution, creating a data fog that may obscure understanding. The functioning human is analogous to a biological factory controlled by an incredibly complex Information and Communication (IC) network. It is proposed that 7 billion computational replicas be made of those 7 billion human IC networks to enable interrogation and manipulation, for understanding and personalized healthcare. This requires a revolutionary ICT that follows the organization of the biological information and communication flows, with implications for hardware, software and connectivity. © Selection and peer-review under responsibility of FET11 conference organizers and published by Elsevier B.V.