Kinetic modelling of glycolytic oscillations

David D. van Niekerk, Morne van Wyk, Theresa Kouril, Jacky L. Snoep*

*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review

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Abstract

Glycolytic oscillations have been studied for well over 60 years, but aspects of their function, and mechanisms of regulation and synchronisation remain unclear. Glycolysis is amenable to mechanistic mathematical modelling, as its components have been well characterised, and the system can be studied at many organisational levels: in vitro reconstituted enzymes, cell free extracts, individual cells, and cell populations. In recent years, the emergence of individual cell analysis has opened new ways of studying this intriguing system.

Original languageEnglish
Article number20230037
Pages (from-to)15-25
Number of pages11
JournalEssays in Biochemistry
Volume68
Issue number1
Early online date30 Apr 2024
DOIs
Publication statusPublished - Apr 2024

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© 2024 The Author(s).

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