TY - GEN
T1 - Knowledge Services Using Rule-Based Formalization for Eligibility Criteria of Clinical Trials
AU - Huang, Z.
AU - Hu, Q.
AU - ten Teije, A.C.M.
AU - van Harmelen, F.A.H.
AU - Ait-Mokhtar, S.
PY - 2016
Y1 - 2016
N2 - Rule-based formalization of eligibility criteria in clinical trials have distinguished features such as declaration, easy maintenance, reusability, and expressiveness. In this paper, we present several knowledge services which can be provided by the rule-based formalization of eligibility criteria. The rule-based formalization can be generated automatically by using the logic programming Prolog with the support of NLP tools for the semantic annotation and relation extraction with medical ontologies/terminologies such as UMLS and SNOMED CT. We show how those automatically generated rule-based formalization for eligibility criteria can be used for the patient recruitment service in SemanticCT, a semantically-enabled system for clinical trials.
AB - Rule-based formalization of eligibility criteria in clinical trials have distinguished features such as declaration, easy maintenance, reusability, and expressiveness. In this paper, we present several knowledge services which can be provided by the rule-based formalization of eligibility criteria. The rule-based formalization can be generated automatically by using the logic programming Prolog with the support of NLP tools for the semantic annotation and relation extraction with medical ontologies/terminologies such as UMLS and SNOMED CT. We show how those automatically generated rule-based formalization for eligibility criteria can be used for the patient recruitment service in SemanticCT, a semantically-enabled system for clinical trials.
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U2 - 10.1007/978-3-319-48335-1_6
DO - 10.1007/978-3-319-48335-1_6
M3 - Conference contribution
SN - 9783319483344
VL - 10038 LNCS
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 49
EP - 61
BT - Health Information Science - 5th International Conference, HIS 2016, Proceedings
PB - Springer/Verlag
T2 - 5th International Conference on Health Information Science, HIS 2016
Y2 - 5 November 2016 through 7 November 2016
ER -