Large-volume injection in gas chromatography-ion trap tandem mass spectrometry for the determination of pesticides in the marine environment at the low ng/l level

R.J.C.A. Steen, I.L. Freriks, W.P. Cofino, U.A.T. Brinkman

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Analytical procedures are developed for the identification and quantification of pesticides in the marine environment. Concentrations in the marine environment are expected to be at or below the low ng/l level, which requires preconcentration of analytes and improved detection. Off-line solid phase extraction (SPE) was combined with large-volume injection gas chromatography (GC) by means of a programmable temperature vaporiser (PTV). The selectivity of the detection procedure was considerably increased by using tandem mass spectrometry (MS/MS) instead of single-MS operation. Two ionisation modes, i.e. electron impact (EI) and positive chemical ionisation (PCI) with acetonitrile as reagent gas, were studied for the determination of five test analytes, i.e. atrazine, desethylatrazine, simazine, alachlor and metolachlor. The detection limits for both ionisation modes were essentially the same, and ranged between 0.2 and 5 ng l
Original languageEnglish
Pages (from-to)153-163
JournalAnalytica Chimica Acta
Volume353
DOIs
Publication statusPublished - 1997

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