Legacy data sharing to improve drug safety assessment: the eTOX project

Ferran Sanz, François Pognan, Thomas Steger-Hartmann, Carlos Díaz, Montserrat Cases, Manuel Pastor, Philippe Marc, Joerg Wichard, Katharine Briggs, David K Watson, Thomas Kleinöder, Chihae Yang, Alexander Amberg, Maria Beaumont, Anthony J Brookes, Søren Brunak, Mark T D Cronin, Gerhard F Ecker, Sylvia Escher, Nigel GreeneAntonio Guzmán, Anne Hersey, Pascale Jacques, Lieve Lammens, Jordi Mestres, Wolfgang Muster, Helle Northeved, Marc Pinches, Javier Saiz, Nicolas Sajot, Alfonso Valencia, Johan van der Lei, Nico P E Vermeulen, Esther Vock, Gerhard Wolber, Ismael Zamora, eTOX

Research output: Contribution to JournalComment / Letter to the editorAcademic

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The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.

Original languageEnglish
Pages (from-to)811-812
Number of pages2
JournalNature Reviews Drug Discovery
Issue number12
Early online date13 Oct 2017
Publication statusPublished - Dec 2017


  • Drug Evaluation, Preclinical
  • Drug Industry
  • Drug-Related Side Effects and Adverse Reactions
  • Humans
  • Information Dissemination
  • Journal Article
  • Risk Assessment


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