Abstract
The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
| Original language | English |
|---|---|
| Pages (from-to) | 811-812 |
| Number of pages | 2 |
| Journal | Nature Reviews Drug Discovery |
| Volume | 16 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 2017 |
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Keywords
- Drug Evaluation, Preclinical
- Drug Industry
- Drug-Related Side Effects and Adverse Reactions
- Humans
- Information Dissemination
- Risk Assessment
- Journal Article
Cite this
}
Legacy data sharing to improve drug safety assessment : the eTOX project. / Sanz, Ferran; Pognan, François; Steger-Hartmann, Thomas; Díaz, Carlos; Cases, Montserrat; Pastor, Manuel; Marc, Philippe; Wichard, Joerg; Briggs, Katharine; Watson, David K; Kleinöder, Thomas; Yang, Chihae; Amberg, Alexander; Beaumont, Maria; Brookes, Anthony J; Brunak, Søren; Cronin, Mark T D; Ecker, Gerhard F; Escher, Sylvia; Greene, Nigel; Guzmán, Antonio; Hersey, Anne; Jacques, Pascale; Lammens, Lieve; Mestres, Jordi; Muster, Wolfgang; Northeved, Helle; Pinches, Marc; Saiz, Javier; Sajot, Nicolas; Valencia, Alfonso; van der Lei, Johan; Vermeulen, Nico P E; Vock, Esther; Wolber, Gerhard; Zamora, Ismael; eTOX.
In: Nature Reviews Drug Discovery, Vol. 16, No. 12, 12.2017, p. 811-812.Research output: Contribution to Journal › Article › Academic › peer-review
TY - JOUR
T1 - Legacy data sharing to improve drug safety assessment
T2 - the eTOX project
AU - Sanz, Ferran
AU - Pognan, François
AU - Steger-Hartmann, Thomas
AU - Díaz, Carlos
AU - Cases, Montserrat
AU - Pastor, Manuel
AU - Marc, Philippe
AU - Wichard, Joerg
AU - Briggs, Katharine
AU - Watson, David K
AU - Kleinöder, Thomas
AU - Yang, Chihae
AU - Amberg, Alexander
AU - Beaumont, Maria
AU - Brookes, Anthony J
AU - Brunak, Søren
AU - Cronin, Mark T D
AU - Ecker, Gerhard F
AU - Escher, Sylvia
AU - Greene, Nigel
AU - Guzmán, Antonio
AU - Hersey, Anne
AU - Jacques, Pascale
AU - Lammens, Lieve
AU - Mestres, Jordi
AU - Muster, Wolfgang
AU - Northeved, Helle
AU - Pinches, Marc
AU - Saiz, Javier
AU - Sajot, Nicolas
AU - Valencia, Alfonso
AU - van der Lei, Johan
AU - Vermeulen, Nico P E
AU - Vock, Esther
AU - Wolber, Gerhard
AU - Zamora, Ismael
AU - eTOX
PY - 2017/12
Y1 - 2017/12
N2 - The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
AB - The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
KW - Drug Evaluation, Preclinical
KW - Drug Industry
KW - Drug-Related Side Effects and Adverse Reactions
KW - Humans
KW - Information Dissemination
KW - Risk Assessment
KW - Journal Article
U2 - 10.1038/nrd.2017.177
DO - 10.1038/nrd.2017.177
M3 - Article
VL - 16
SP - 811
EP - 812
JO - Nature Reviews Drug Discovery
JF - Nature Reviews Drug Discovery
SN - 1474-1776
IS - 12
ER -