Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics

R.A. Smits; H.D. Lim; T.K. van der Meer; S. Kuhne; K Bessembinder; O.P. Zuiderveld; M. Wijtmans; I.J.P. de Esch; R. Leurs

doi:10.1016/j.bmcl.2011.10.104

Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics

R.A. Smits, H.D. Lim, T.K. van der Meer, S. Kuhne, K Bessembinder, O.P. Zuiderveld, M. Wijtmans, I.J.P. de Esch, R. Leurs

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The histamine H

Original language	English
Pages (from-to)	461-467
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	22
DOIs	https://doi.org/10.1016/j.bmcl.2011.10.104
Publication status	Published - 2012

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10.1016/j.bmcl.2011.10.104

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@article{d3635127dafe448385b05c1b64a60c7f,

title = "Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics",

abstract = "The histamine H",

author = "R.A. Smits and H.D. Lim and {van der Meer}, T.K. and S. Kuhne and K Bessembinder and O.P. Zuiderveld and M. Wijtmans and {de Esch}, I.J.P. and R. Leurs",

year = "2012",

doi = "10.1016/j.bmcl.2011.10.104",

language = "English",

volume = "22",

pages = "461--467",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

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TY - JOUR

T1 - Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics

AU - Smits, R.A.

AU - Lim, H.D.

AU - van der Meer, T.K.

AU - Kuhne, S.

AU - Bessembinder, K

AU - Zuiderveld, O.P.

AU - Wijtmans, M.

AU - de Esch, I.J.P.

AU - Leurs, R.

PY - 2012

Y1 - 2012

N2 - The histamine H

AB - The histamine H

U2 - 10.1016/j.bmcl.2011.10.104

DO - 10.1016/j.bmcl.2011.10.104

M3 - Article

SN - 0960-894X

VL - 22

SP - 461

EP - 467

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

ER -

Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics

Abstract

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