Ligand-directed biased agonism at human histamine H₃ receptor isoforms across Gα_i/o- and β-arrestin2-mediated pathways

Pharmacology, Toxicology and Pharmaceutical Science

• Histamine H3 Receptor 100%
• Neurologic Disease 66%
• G Protein Coupled Receptor 66%
• Disease 66%
• Side Effect 33%
• Neurotransmitter 33%
• Guanine Nucleotide Binding Protein 33%
• Histamine H3 Receptor Agonist 33%
• Sulfur 35 33%
• Histamine 33%
• Alzheimer's Disease 33%
• Parkinson's Disease 33%
• Serotonin 33%
• Neurotransmitter Receptor 33%

Neuroscience

• Histamine H3 Receptor 100%
• G Protein Coupled Receptor 50%
• Parkinson's Disease 25%
• Biased Ligands 25%
• Histamine 25%
• Dementia Praecox 25%
• G Protein 25%
• Serotonin 25%
• Neurotransmitter 25%
• Receptor Agonists 25%
• Cyclic Adenosine Monophosphate 25%
• Neurological Disorder 25%
• Agonist 25%
• Alzheimer's Disease 25%
• Neurotransmitter Receptor 25%
• RNA Splicing 25%

Biochemistry, Genetics and Molecular Biology

• Isoform 100%
• Histamine H3 Receptor 100%
• G Protein Coupled Receptor 20%
• Histamine 10%
• G Protein 10%
• Serotonin 10%
• Neurotransmitter 10%
• RNA Splicing 10%
• Homeostasis 10%
• Physiological Process 10%
• Agonist 10%
• Biased Ligands 10%
• Receptor Agonists 10%
• Neuropharmacology 10%
• Cyclic Adenosine Monophosphate 10%
• Neurotransmitter Receptor 10%