Long-term effects of amyloid, hypometabolism, and atrophy on neuropsychological functions

R. Ossenkoppele, W.M. van der Flier, S.C.J. Verfaillie, H. Vrenken, A. Versteeg, R.A. van Schijndel, S.A. Sikkes, J. Twisk, S.M. Adriaanse, M.D. Zwan, R. Boellaard, A.D. Windhorst, F. Barkhof, P. Scheltens, A.A. Lammertsma, B.N.M. van Berckel

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Objective: To assess how amyloid deposition, glucose hypometabolism, and cerebral atrophy affect neuropsychological performance in patients with Alzheimer disease (AD) dementia, patients with mild cognitive impairment (MCI), and controls over time. Methods: A total of 41 patients with AD dementia, 28 patients with MCI, and 19 controls underwent [
Original languageEnglish
Pages (from-to)1768-1775
JournalNeurology
Volume82
Issue number20
DOIs
Publication statusPublished - 2014

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