We present a novel approach for determining the strength of the electric field experienced by proteins immobilised on membrane models. It is based on the vibrational Stark effect of a nitrile label introduced at different positions on engineered proteins and monitored by surface enhanced infrared absorption spectroscopy. © 2012 The Royal Society of Chemistry.
Schkolnik, G., Utesch, T., Salewski, J., Tenger, K., Millo, D., Kranich, A., ... Hildebrandt, P. (2012). Mapping local electric fields in proteins at biomimetic interfaces. Chemical Commununications, 48, 70-72. https://doi.org/10.1039/c1cc13186a