Mass Spectrometry-based bioassay for the screening of soluble orphan receptors

D.A. van Elswijk, U.R. Tjaden, J de Greef, H. Irth

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

The suitability of a novel mass spectrometric (MS) based flow-injection bioassay format to rapidly detect ligands for soluble orphan receptors in complex matrices was demonstrated, using digoxin and antidigoxigenin FAb as the model ligand and the model protein target, respectively. In addition, characteristic MS and MS
Original languageEnglish
Pages (from-to)625-636
JournalInternational Journal of Mass Spectrometry
Volume210-211
DOIs
Publication statusPublished - 2001

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