Mass Spectrometry-based bioassay for the screening of soluble orphan receptors

D.A. van Elswijk; U.R. Tjaden; J de Greef; H. Irth

doi:10.1016/S1387-3806(01)00445-6

Mass Spectrometry-based bioassay for the screening of soluble orphan receptors

D.A. van Elswijk
, U.R. Tjaden
, J de Greef
, H. Irth

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The suitability of a novel mass spectrometric (MS) based flow-injection bioassay format to rapidly detect ligands for soluble orphan receptors in complex matrices was demonstrated, using digoxin and antidigoxigenin FAb as the model ligand and the model protein target, respectively. In addition, characteristic MS and MS

Original language	English
Pages (from-to)	625-636
Journal	International Journal of Mass Spectrometry
Volume	210-211
DOIs	https://doi.org/10.1016/S1387-3806(01)00445-6
Publication status	Published - 2001

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SDG 6 Clean Water and Sanitation

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10.1016/S1387-3806(01)00445-6

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title = "Mass Spectrometry-based bioassay for the screening of soluble orphan receptors",

abstract = "The suitability of a novel mass spectrometric (MS) based flow-injection bioassay format to rapidly detect ligands for soluble orphan receptors in complex matrices was demonstrated, using digoxin and antidigoxigenin FAb as the model ligand and the model protein target, respectively. In addition, characteristic MS and MS",

author = "\{van Elswijk\}, D.A. and U.R. Tjaden and \{de Greef\}, J and H. Irth",

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AU - van Elswijk, D.A.

AU - Tjaden, U.R.

AU - de Greef, J

AU - Irth, H.

PY - 2001

Y1 - 2001

N2 - The suitability of a novel mass spectrometric (MS) based flow-injection bioassay format to rapidly detect ligands for soluble orphan receptors in complex matrices was demonstrated, using digoxin and antidigoxigenin FAb as the model ligand and the model protein target, respectively. In addition, characteristic MS and MS

AB - The suitability of a novel mass spectrometric (MS) based flow-injection bioassay format to rapidly detect ligands for soluble orphan receptors in complex matrices was demonstrated, using digoxin and antidigoxigenin FAb as the model ligand and the model protein target, respectively. In addition, characteristic MS and MS

U2 - 10.1016/S1387-3806(01)00445-6

DO - 10.1016/S1387-3806(01)00445-6

M3 - Article

SN - 1387-3806

VL - 210-211

SP - 625

EP - 636

JO - International Journal of Mass Spectrometry

JF - International Journal of Mass Spectrometry

ER -

Mass Spectrometry-based bioassay for the screening of soluble orphan receptors

Abstract

UN SDGs

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