TY - JOUR
T1 - Maximum parsimony distance on phylogenetic trees
T2 - A linear kernel and constant factor approximation algorithm
AU - Jones, Mark
AU - Kelk, Steven
AU - Stougie, Leen
PY - 2021/5
Y1 - 2021/5
N2 - Maximum parsimony distance is a measure used to quantify the dissimilarity of two unrooted phylogenetic trees. It is NP-hard to compute, and very few positive algorithmic results are known due to its complex combinatorial structure. Here we address this shortcoming by showing that the problem is fixed parameter tractable. We do this by establishing a linear kernel i.e., that after applying certain reduction rules the resulting instance has size that is bounded by a linear function of the distance. As powerful corollaries to this result we prove that the problem permits a polynomial-time constant-factor approximation algorithm; that the treewidth of a natural auxiliary graph structure encountered in phylogenetics is bounded by a function of the distance; and that the distance is within a constant factor of the size of a maximum agreement forest of the two trees, a well studied object in phylogenetics.
AB - Maximum parsimony distance is a measure used to quantify the dissimilarity of two unrooted phylogenetic trees. It is NP-hard to compute, and very few positive algorithmic results are known due to its complex combinatorial structure. Here we address this shortcoming by showing that the problem is fixed parameter tractable. We do this by establishing a linear kernel i.e., that after applying certain reduction rules the resulting instance has size that is bounded by a linear function of the distance. As powerful corollaries to this result we prove that the problem permits a polynomial-time constant-factor approximation algorithm; that the treewidth of a natural auxiliary graph structure encountered in phylogenetics is bounded by a function of the distance; and that the distance is within a constant factor of the size of a maximum agreement forest of the two trees, a well studied object in phylogenetics.
KW - Fixed parameter tractability
KW - Maximum agreement forest
KW - Maximum parsimony
KW - Phylogenetics
UR - http://www.scopus.com/inward/record.url?scp=85097648036&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85097648036&partnerID=8YFLogxK
U2 - 10.1016/j.jcss.2020.10.003
DO - 10.1016/j.jcss.2020.10.003
M3 - Article
AN - SCOPUS:85097648036
SN - 0022-0000
VL - 117
SP - 165
EP - 181
JO - Journal of Computer and System Sciences
JF - Journal of Computer and System Sciences
ER -