Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29

Anja van der Hout, Koen I Neijenhuijs, Femke Jansen, Cornelia F van Uden-Kraan, Neil K Aaronson, Mogens Groenvold, Bernhard Holzner, Caroline B Terwee, Lonneke V van de Poll-Franse, Pim Cuijpers, Irma M Verdonck-de Leeuw

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.

METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.

RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.

CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.

LanguageEnglish
JournalSupportive Care in Cancer
DOIs
Publication statusE-pub ahead of print - 13 Apr 2019

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Colorectal Neoplasms
Quality of Life
Research
Health
Patient Reported Outcome Measures

Cite this

@article{db669f8cf8634938b0509e5762fabf14,
title = "Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29",
abstract = "INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as {"}sufficient,{"} with low evidence. Reliability was rated as {"}insufficient,{"} with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as {"}inconsistent,{"} with moderate evidence. Structural validity, measurement error, and responsiveness were rated as {"}indeterminate{"} and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.",
author = "{van der Hout}, Anja and Neijenhuijs, {Koen I} and Femke Jansen and {van Uden-Kraan}, {Cornelia F} and Aaronson, {Neil K} and Mogens Groenvold and Bernhard Holzner and Terwee, {Caroline B} and {van de Poll-Franse}, {Lonneke V} and Pim Cuijpers and {Verdonck-de Leeuw}, {Irma M}",
year = "2019",
month = "4",
day = "13",
doi = "10.1007/s00520-019-04764-7",
language = "English",
journal = "Supportive Care in Cancer",
issn = "0941-4355",
publisher = "Springer Verlag",

}

Measuring health-related quality of life in colorectal cancer patients : systematic review of measurement properties of the EORTC QLQ-CR29. / van der Hout, Anja; Neijenhuijs, Koen I; Jansen, Femke; van Uden-Kraan, Cornelia F; Aaronson, Neil K; Groenvold, Mogens; Holzner, Bernhard; Terwee, Caroline B; van de Poll-Franse, Lonneke V; Cuijpers, Pim; Verdonck-de Leeuw, Irma M.

In: Supportive Care in Cancer, 13.04.2019.

Research output: Contribution to JournalReview articleAcademicpeer-review

TY - JOUR

T1 - Measuring health-related quality of life in colorectal cancer patients

T2 - Supportive Care in Cancer

AU - van der Hout, Anja

AU - Neijenhuijs, Koen I

AU - Jansen, Femke

AU - van Uden-Kraan, Cornelia F

AU - Aaronson, Neil K

AU - Groenvold, Mogens

AU - Holzner, Bernhard

AU - Terwee, Caroline B

AU - van de Poll-Franse, Lonneke V

AU - Cuijpers, Pim

AU - Verdonck-de Leeuw, Irma M

PY - 2019/4/13

Y1 - 2019/4/13

N2 - INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.

AB - INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.

U2 - 10.1007/s00520-019-04764-7

DO - 10.1007/s00520-019-04764-7

M3 - Review article

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

SN - 0941-4355

ER -