Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29

Anja van der Hout; Koen I. Neijenhuijs; Femke Jansen; Cornelia F. van Uden-Kraan; Neil K. Aaronson; Mogens Groenvold; Bernhard Holzner; Caroline B. Terwee; Lonneke V. van de Poll-Franse; Pim Cuijpers; Irma M. Verdonck-de Leeuw

doi:10.1007/s00520-019-04764-7

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29

Anja van der Hout
, Koen I. Neijenhuijs
, Femke Jansen
, Cornelia F. van Uden-Kraan
, Neil K. Aaronson
, Mogens Groenvold
, Bernhard Holzner
, Caroline B. Terwee
, Lonneke V. van de Poll-Franse
, Pim Cuijpers
, Irma M. Verdonck-de Leeuw^*

^*Corresponding author for this work

Research output: Contribution to Journal › Review article › Academic › peer-review

Abstract

INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.

METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.

RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.

CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.

Original language	English
Pages (from-to)	2395-2412
Number of pages	18
Journal	Supportive Care in Cancer
Volume	27
Issue number	7
Early online date	13 Apr 2019
DOIs	https://doi.org/10.1007/s00520-019-04764-7
Publication status	Published - 1 Jul 2019

Funding

Funder number
???publication-publication-funding-organisation-not-added???	16872

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Colorectal cancer
EORTC QLQ-CR29
Health-related quality of life
Measurement property
Patient-reported outcome measure (PROM)
Systematic review

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10.1007/s00520-019-04764-7

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van der Hout, A., Neijenhuijs, K. I., Jansen, F., van Uden-Kraan, C. F., Aaronson, N. K., Groenvold, M., Holzner, B., Terwee, C. B., van de Poll-Franse, L. V., Cuijpers, P., & Verdonck-de Leeuw, I. M. (2019). Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29. Supportive Care in Cancer, 27(7), 2395-2412. https://doi.org/10.1007/s00520-019-04764-7

@article{db669f8cf8634938b0509e5762fabf14,

title = "Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29",

abstract = "INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as {"}sufficient,{"} with low evidence. Reliability was rated as {"}insufficient,{"} with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as {"}inconsistent,{"} with moderate evidence. Structural validity, measurement error, and responsiveness were rated as {"}indeterminate{"} and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.",

keywords = "Colorectal cancer, EORTC QLQ-CR29, Health-related quality of life, Measurement property, Patient-reported outcome measure (PROM), Systematic review",

author = "\{van der Hout\}, Anja and Neijenhuijs, \{Koen I.\} and Femke Jansen and \{van Uden-Kraan\}, \{Cornelia F.\} and Aaronson, \{Neil K.\} and Mogens Groenvold and Bernhard Holzner and Terwee, \{Caroline B.\} and \{van de Poll-Franse\}, \{Lonneke V.\} and Pim Cuijpers and \{Verdonck-de Leeuw\}, \{Irma M.\}",

year = "2019",

month = jul,

day = "1",

doi = "10.1007/s00520-019-04764-7",

language = "English",

volume = "27",

pages = "2395--2412",

journal = "Supportive Care in Cancer",

issn = "0941-4355",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "7",

}

van der Hout, A, Neijenhuijs, KI, Jansen, F, van Uden-Kraan, CF, Aaronson, NK, Groenvold, M, Holzner, B, Terwee, CB, van de Poll-Franse, LV, Cuijpers, P & Verdonck-de Leeuw, IM 2019, 'Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29', Supportive Care in Cancer, vol. 27, no. 7, pp. 2395-2412. https://doi.org/10.1007/s00520-019-04764-7

TY - JOUR

T1 - Measuring health-related quality of life in colorectal cancer patients

T2 - systematic review of measurement properties of the EORTC QLQ-CR29

AU - van der Hout, Anja

AU - Neijenhuijs, Koen I.

AU - Jansen, Femke

AU - van Uden-Kraan, Cornelia F.

AU - Aaronson, Neil K.

AU - Groenvold, Mogens

AU - Holzner, Bernhard

AU - Terwee, Caroline B.

AU - van de Poll-Franse, Lonneke V.

AU - Cuijpers, Pim

AU - Verdonck-de Leeuw, Irma M.

PY - 2019/7/1

Y1 - 2019/7/1

N2 - INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.

AB - INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.

KW - Colorectal cancer

KW - EORTC QLQ-CR29

KW - Health-related quality of life

KW - Measurement property

KW - Patient-reported outcome measure (PROM)

KW - Systematic review

UR - https://www.scopus.com/pages/publications/85064518774

UR - https://www.scopus.com/pages/publications/85064518774#tab=citedBy

U2 - 10.1007/s00520-019-04764-7

DO - 10.1007/s00520-019-04764-7

M3 - Review article

C2 - 30982095

SN - 0941-4355

VL - 27

SP - 2395

EP - 2412

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

IS - 7

ER -

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29

Abstract

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UN SDGs

Keywords

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