Mechanical stimulation of bone cells using fluid flow

C. Huesa, A.D. Bakker

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

This chapter describes several methods suitable for mechanically stimulating monolayers of bone cells by fluid shear stress (FSS) in vitro. Fluid flow is generated by pumping culture medium through two parallel plates, one of which contains a monolayer of cells. Methods for measuring nitric oxide production by bone cells in response to FSS are also described.
Original languageEnglish
Pages (from-to)573-592
JournalMethods in Molecular Biology
Volume816
DOIs
Publication statusPublished - 2012

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