Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

E.M. van Leeuwen; A. Sabo; J.C. Bis; J.E. Huffman; A. Manichaikul; A.V. Smith; M.F. Feitosa; S. Demissie; P.K. Joshi; Q. Duan; J. Marten; J.B. van Klinken; I. Surakka; I.M. Nolte; W. Zhang; H. Mbarek; R. Li-Gao; S. Trompet; N. Verweij; E. Evangelou; L.P. Lyytikäinen; B.O. Tayo; J. Deelen; P.J. van der Most; S.W. van der Laan; D.E. Arking; A. Morrison; A. Dehghan; O.H. Franco; A. Hofman; F. Rivadeneira; E.J. Sijbrands; A.G. Uitterlinden; J.C. Mychaleckyi; A. Campbell; L.J. Hocking; S. Padmanabhan; J.A. Brody; K.M. Rice; C.C. White; T. Harris; A. Isaacs; H. Campbell; L.A. Lange; I. Rudan; I. Kolcic; P. Navarro; T. Zemunik; V. Salomaa; A.S. Kooner; J.S. Kooner; B. Lehne; W.R. Scott; S.T. Tan; E.J.C. de Geus; Y. Milaneschi; B.W.J.H. Penninx; G. Willemsen; R. de Mutsert; I. Ford; R.T. Gansevoort; M.P. Segura-Lepe; O.T. Raitakari; J.S. Viikari; K. Nikus; T. Forrester; C.A. McKenzie; A.J. de Craen; H.M. den Ruijter; G. Pasterkamp; H. Snieder; A.J. Oldehinkel; P.E. Slagboom; R.S. Cooper; M. Kähönen; T. Lehtimäki; P. Elliott; P. van der Harst; J.W. Jukema; D.O. Mook-Kanamori; D.I. Boomsma; J.C. Chambers; M.A. Swertz; S. Ripatti; K. Willems van Dijk; V. Vitart; O. Polasek; C. Hayward; J.G. Wilson; J.F. Wilson; V. Gudnason; S.S. Rich; B.M. Psaty; I.B. Borecki; E. Boerwinkle; J.I. Rotter; L.A. Cupples; C.M. van Duijn

doi:10.1136/jmedgenet-2015-103439

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

E.M. van Leeuwen, A. Sabo, J.C. Bis, J.E. Huffman, A. Manichaikul, A.V. Smith, M.F. Feitosa, S. Demissie, P.K. Joshi, Q. Duan, J. Marten, J.B. van Klinken, I. Surakka, I.M. Nolte, W. Zhang, H. Mbarek, R. Li-Gao, S. Trompet, N. Verweij, E. EvangelouL.P. Lyytikäinen, B.O. Tayo, J. Deelen, P.J. van der Most, S.W. van der Laan, D.E. Arking, A. Morrison, A. Dehghan, O.H. Franco, A. Hofman, F. Rivadeneira, E.J. Sijbrands, A.G. Uitterlinden, J.C. Mychaleckyi, A. Campbell, L.J. Hocking, S. Padmanabhan, J.A. Brody, K.M. Rice, C.C. White, T. Harris, A. Isaacs, H. Campbell, L.A. Lange, I. Rudan, I. Kolcic, P. Navarro, T. Zemunik, V. Salomaa, A.S. Kooner, J.S. Kooner, B. Lehne, W.R. Scott, S.T. Tan, E.J.C. de Geus, Y. Milaneschi, B.W.J.H. Penninx, G. Willemsen, R. de Mutsert, I. Ford, R.T. Gansevoort, M.P. Segura-Lepe, O.T. Raitakari, J.S. Viikari, K. Nikus, T. Forrester, C.A. McKenzie, A.J. de Craen, H.M. den Ruijter, G. Pasterkamp, H. Snieder, A.J. Oldehinkel, P.E. Slagboom, R.S. Cooper, M. Kähönen, T. Lehtimäki, P. Elliott, P. van der Harst, J.W. Jukema, D.O. Mook-Kanamori, D.I. Boomsma, J.C. Chambers, M.A. Swertz, S. Ripatti, K. Willems van Dijk, V. Vitart, O. Polasek, C. Hayward, J.G. Wilson, J.F. Wilson, V. Gudnason, S.S. Rich, B.M. Psaty, I.B. Borecki, E. Boerwinkle, J.I. Rotter, L.A. Cupples, C.M. van Duijn

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Original language	English
Pages (from-to)	441-449
Journal	Journal of Medical Genetics
Volume	53
Issue number	7
DOIs	https://doi.org/10.1136/jmedgenet-2015-103439
Publication status	Published - 2016

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van Leeuwen, E. M., Sabo, A., Bis, J. C., Huffman, J. E., Manichaikul, A., Smith, A. V., Feitosa, M. F., Demissie, S., Joshi, P. K., Duan, Q., Marten, J., van Klinken, J. B., Surakka, I., Nolte, I. M., Zhang, W., Mbarek, H., Li-Gao, R., Trompet, S., Verweij, N., ... van Duijn, C. M. (2016). Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics, 53(7), 441-449. https://doi.org/10.1136/jmedgenet-2015-103439

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title = "Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels",

author = "{van Leeuwen}, E.M. and A. Sabo and J.C. Bis and J.E. Huffman and A. Manichaikul and A.V. Smith and M.F. Feitosa and S. Demissie and P.K. Joshi and Q. Duan and J. Marten and {van Klinken}, J.B. and I. Surakka and I.M. Nolte and W. Zhang and H. Mbarek and R. Li-Gao and S. Trompet and N. Verweij and E. Evangelou and L.P. Lyytik{\"a}inen and B.O. Tayo and J. Deelen and {van der Most}, P.J. and {van der Laan}, S.W. and D.E. Arking and A. Morrison and A. Dehghan and O.H. Franco and A. Hofman and F. Rivadeneira and E.J. Sijbrands and A.G. Uitterlinden and J.C. Mychaleckyi and A. Campbell and L.J. Hocking and S. Padmanabhan and J.A. Brody and K.M. Rice and C.C. White and T. Harris and A. Isaacs and H. Campbell and L.A. Lange and I. Rudan and I. Kolcic and P. Navarro and T. Zemunik and V. Salomaa and A.S. Kooner and J.S. Kooner and B. Lehne and W.R. Scott and S.T. Tan and {de Geus}, E.J.C. and Y. Milaneschi and B.W.J.H. Penninx and G. Willemsen and {de Mutsert}, R. and I. Ford and R.T. Gansevoort and M.P. Segura-Lepe and O.T. Raitakari and J.S. Viikari and K. Nikus and T. Forrester and C.A. McKenzie and {de Craen}, A.J. and {den Ruijter}, H.M. and G. Pasterkamp and H. Snieder and A.J. Oldehinkel and P.E. Slagboom and R.S. Cooper and M. K{\"a}h{\"o}nen and T. Lehtim{\"a}ki and P. Elliott and {van der Harst}, P. and J.W. Jukema and D.O. Mook-Kanamori and D.I. Boomsma and J.C. Chambers and M.A. Swertz and S. Ripatti and {Willems van Dijk}, K. and V. Vitart and O. Polasek and C. Hayward and J.G. Wilson and J.F. Wilson and V. Gudnason and S.S. Rich and B.M. Psaty and I.B. Borecki and E. Boerwinkle and J.I. Rotter and L.A. Cupples and {van Duijn}, C.M.",

year = "2016",

doi = "10.1136/jmedgenet-2015-103439",

language = "English",

volume = "53",

pages = "441--449",

journal = "Journal of Medical Genetics",

issn = "0022-2593",

publisher = "BMJ Publishing Group",

number = "7",

}

van Leeuwen, EM, Sabo, A, Bis, JC, Huffman, JE, Manichaikul, A, Smith, AV, Feitosa, MF, Demissie, S, Joshi, PK, Duan, Q, Marten, J, van Klinken, JB, Surakka, I, Nolte, IM, Zhang, W, Mbarek, H, Li-Gao, R, Trompet, S, Verweij, N, Evangelou, E, Lyytikäinen, LP, Tayo, BO, Deelen, J, van der Most, PJ, van der Laan, SW, Arking, DE, Morrison, A, Dehghan, A, Franco, OH, Hofman, A, Rivadeneira, F, Sijbrands, EJ, Uitterlinden, AG, Mychaleckyi, JC, Campbell, A, Hocking, LJ, Padmanabhan, S, Brody, JA, Rice, KM, White, CC, Harris, T, Isaacs, A, Campbell, H, Lange, LA, Rudan, I, Kolcic, I, Navarro, P, Zemunik, T, Salomaa, V, Kooner, AS, Kooner, JS, Lehne, B, Scott, WR, Tan, ST, de Geus, EJC, Milaneschi, Y, Penninx, BWJH, Willemsen, G, de Mutsert, R, Ford, I, Gansevoort, RT, Segura-Lepe, MP, Raitakari, OT, Viikari, JS, Nikus, K, Forrester, T, McKenzie, CA, de Craen, AJ, den Ruijter, HM, Pasterkamp, G, Snieder, H, Oldehinkel, AJ, Slagboom, PE, Cooper, RS, Kähönen, M, Lehtimäki, T, Elliott, P, van der Harst, P, Jukema, JW, Mook-Kanamori, DO, Boomsma, DI, Chambers, JC, Swertz, MA, Ripatti, S, Willems van Dijk, K, Vitart, V, Polasek, O, Hayward, C, Wilson, JG, Wilson, JF, Gudnason, V, Rich, SS, Psaty, BM, Borecki, IB, Boerwinkle, E, Rotter, JI, Cupples, LA & van Duijn, CM 2016, 'Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels', Journal of Medical Genetics, vol. 53, no. 7, pp. 441-449. https://doi.org/10.1136/jmedgenet-2015-103439

TY - JOUR

T1 - Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

AU - van Leeuwen, E.M.

AU - Sabo, A.

AU - Bis, J.C.

AU - Huffman, J.E.

AU - Manichaikul, A.

AU - Smith, A.V.

AU - Feitosa, M.F.

AU - Demissie, S.

AU - Joshi, P.K.

AU - Duan, Q.

AU - Marten, J.

AU - van Klinken, J.B.

AU - Surakka, I.

AU - Nolte, I.M.

AU - Zhang, W.

AU - Mbarek, H.

AU - Li-Gao, R.

AU - Trompet, S.

AU - Verweij, N.

AU - Evangelou, E.

AU - Lyytikäinen, L.P.

AU - Tayo, B.O.

AU - Deelen, J.

AU - van der Most, P.J.

AU - van der Laan, S.W.

AU - Arking, D.E.

AU - Morrison, A.

AU - Dehghan, A.

AU - Franco, O.H.

AU - Hofman, A.

AU - Rivadeneira, F.

AU - Sijbrands, E.J.

AU - Uitterlinden, A.G.

AU - Mychaleckyi, J.C.

AU - Campbell, A.

AU - Hocking, L.J.

AU - Padmanabhan, S.

AU - Brody, J.A.

AU - Rice, K.M.

AU - White, C.C.

AU - Harris, T.

AU - Isaacs, A.

AU - Campbell, H.

AU - Lange, L.A.

AU - Rudan, I.

AU - Kolcic, I.

AU - Navarro, P.

AU - Zemunik, T.

AU - Salomaa, V.

AU - Kooner, A.S.

AU - Kooner, J.S.

AU - Lehne, B.

AU - Scott, W.R.

AU - Tan, S.T.

AU - de Geus, E.J.C.

AU - Milaneschi, Y.

AU - Penninx, B.W.J.H.

AU - Willemsen, G.

AU - de Mutsert, R.

AU - Ford, I.

AU - Gansevoort, R.T.

AU - Segura-Lepe, M.P.

AU - Raitakari, O.T.

AU - Viikari, J.S.

AU - Nikus, K.

AU - Forrester, T.

AU - McKenzie, C.A.

AU - de Craen, A.J.

AU - den Ruijter, H.M.

AU - Pasterkamp, G.

AU - Snieder, H.

AU - Oldehinkel, A.J.

AU - Slagboom, P.E.

AU - Cooper, R.S.

AU - Kähönen, M.

AU - Lehtimäki, T.

AU - Elliott, P.

AU - van der Harst, P.

AU - Jukema, J.W.

AU - Mook-Kanamori, D.O.

AU - Boomsma, D.I.

AU - Chambers, J.C.

AU - Swertz, M.A.

AU - Ripatti, S.

AU - Willems van Dijk, K.

AU - Vitart, V.

AU - Polasek, O.

AU - Hayward, C.

AU - Wilson, J.G.

AU - Wilson, J.F.

AU - Gudnason, V.

AU - Rich, S.S.

AU - Psaty, B.M.

AU - Borecki, I.B.

AU - Boerwinkle, E.

AU - Rotter, J.I.

AU - Cupples, L.A.

AU - van Duijn, C.M.

PY - 2016

Y1 - 2016

U2 - 10.1136/jmedgenet-2015-103439

DO - 10.1136/jmedgenet-2015-103439

M3 - Article

SN - 0022-2593

VL - 53

SP - 441

EP - 449

JO - Journal of Medical Genetics

JF - Journal of Medical Genetics

IS - 7

ER -