Metabolite Depletion Affects Flux Profiling of Cell Lines

A. Nilsson, J. R. Haanstra, B. Teusink, J. Nielsen*

*Corresponding author for this work

Research output: Contribution to JournalShort surveyAcademicpeer-review

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Abstract

Quantifying the rate of consumption and release of metabolites (i.e., flux profiling) has become integral to the study of cancer. The fluxes as well as the growth of the cells may be affected by metabolite depletion during cultivation.

Original languageEnglish
Pages (from-to)395-397
Number of pages3
JournalTrends in Biochemical Sciences
Volume43
Issue number6
Early online date12 Apr 2018
DOIs
Publication statusPublished - Jun 2018

Keywords

  • cancer
  • glutamine
  • metabolic modeling
  • serine

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