TY - JOUR
T1 - Metabolomics technologies and metabolite identification
AU - Moco, S.
AU - Vervoort, J.
AU - Moco, S.
AU - Bino, R.J.
AU - De Vos, R.C.H.
AU - Bino, R.
PY - 2007/10/1
Y1 - 2007/10/1
N2 - Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites) present in a biological system. Most commonly, metabolomics is heavily supported by mass spectrometry (MS) and nuclear magnetic resonance (NMR) as parallel technologies that provide an overview of the metabolome and high-power compound elucidation. Over and above large-scale analysis, a major effort is needed for unequivocal identification of metabolites. The combination of liquid chromatography (LC)-MS and NMR is a powerful methodology for identifying metabolites. Better chemical characterization of the metabolome will undoubtedly enlarge knowledge of any biological system. © 2007 Elsevier Ltd. All rights reserved.
AB - Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites) present in a biological system. Most commonly, metabolomics is heavily supported by mass spectrometry (MS) and nuclear magnetic resonance (NMR) as parallel technologies that provide an overview of the metabolome and high-power compound elucidation. Over and above large-scale analysis, a major effort is needed for unequivocal identification of metabolites. The combination of liquid chromatography (LC)-MS and NMR is a powerful methodology for identifying metabolites. Better chemical characterization of the metabolome will undoubtedly enlarge knowledge of any biological system. © 2007 Elsevier Ltd. All rights reserved.
UR - https://www.scopus.com/pages/publications/34948814692
UR - https://www.scopus.com/inward/citedby.url?scp=34948814692&partnerID=8YFLogxK
U2 - 10.1016/j.trac.2007.08.003
DO - 10.1016/j.trac.2007.08.003
M3 - Article
SN - 0165-9936
VL - 26
SP - 855
EP - 866
JO - TrAC - Trends in Analytical Chemistry
JF - TrAC - Trends in Analytical Chemistry
IS - 9
ER -