Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections

Loreto Oyarte Gálvez; Arjan Fraters; Herman L. Offerhaus; Michel Versluis; Ian W. Hunter; David Fernández Rivas

doi:10.1063/1.5140264

Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections

Loreto Oyarte Gálvez, Arjan Fraters, Herman L. Offerhaus, Michel Versluis, Ian W. Hunter, David Fernández Rivas^*

^*Corresponding author for this work

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding liquid is expelled from the constraining microfluidic channel through a nozzle, creating a jet. The characteristics of the resulting liquid jet were imaged using ultra-fast imaging techniques. Here, we provide a phenomenological description of the jet shapes and velocities and compare them with a boundary integral numerical model. We define the parameter regime, varying jet speed, taper geometry, and liquid volume for optimal printing, injection, and spray applications. These results are important for the design of energy-efficient needle-free jet injectors based on microfluidic thermocavitation.

Original language	English
Article number	104901
Pages (from-to)	1-11
Number of pages	11
Journal	Journal of Applied Physics
Volume	127
Issue number	10
DOIs	https://doi.org/10.1063/1.5140264
Publication status	Published - 10 Mar 2020
Externally published	Yes

Funding

We would like to thank Stefan Schlautmann and Frans Segerink for their technical support during fabrication and optical setup construction. We also thank James W. Bales from the MIT Edgerton’s center for access to the Phantom high-speed camera and illumination. A.F. and M.V. acknowledge the program High Tech Systems and Materials (HTSM) with Project No. 12802. D.F.R. acknowledges the recognition from the Royal Dutch Society of Sciences (KHMW) that granted the Pieter Langerhuizen Lambertuszoon Fonds, 2016.

Funders	Funder number
Pieter Langerhuizen Lambertuszoon Fonds
Royal Society

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1063/1.5140264

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abstract = "Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding liquid is expelled from the constraining microfluidic channel through a nozzle, creating a jet. The characteristics of the resulting liquid jet were imaged using ultra-fast imaging techniques. Here, we provide a phenomenological description of the jet shapes and velocities and compare them with a boundary integral numerical model. We define the parameter regime, varying jet speed, taper geometry, and liquid volume for optimal printing, injection, and spray applications. These results are important for the design of energy-efficient needle-free jet injectors based on microfluidic thermocavitation.",

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AU - Oyarte Gálvez, Loreto

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AU - Offerhaus, Herman L.

AU - Versluis, Michel

AU - Hunter, Ian W.

AU - Fernández Rivas, David

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Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections

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