Microglial activation in healthy aging

A. Schuitemaker, T.F. van der Doef, R. Boellaard, W.M. van der Flier, M.M. Yaqub, A.D. Windhorst, F. Barkhof, C. Jonker, R.W. Kloet, A.A. Lammertsma, P. Scheltens, B.N.M. van Berckel

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Healthy brain aging is characterized by neuronal loss and decline of cognitive function. Neuronal loss is closely associated with microglial activation and postmortem studies have indeed suggested that activated microglia may be present in the aging brain. Microglial activation can be quantified in vivo using (R)-[
    Original languageEnglish
    Pages (from-to)1067-1072
    JournalNeurobiology of Aging
    Volume33
    Issue number6
    DOIs
    Publication statusPublished - 2012

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