TY - JOUR
T1 - Migraine mutations impair hippocampal learning despite enhanced long-term potentiation.
AU - Dilekoz, E.
AU - Houben, T.
AU - Eikermann-Hearter, K.
AU - Balkaya, M.
AU - Lenselink, A.M.
AU - Whalen, M.J.
AU - Spijker, S.
AU - Ferrari, M.D.
AU - van den Maagdenberg, A.M.J.M.
AU - Ayate, C.
PY - 2015
Y1 - 2015
N2 - To explain cognitive and memory difficulties observed in some familial hemiplegic migraine (FHM) patients, we examined hippocampal neurotransmission and plasticity in knock-in mice expressing theFHMtype 1 (FHM1) R192Q gain-of function mutation in the CACNA1A gene that encodes the α
AB - To explain cognitive and memory difficulties observed in some familial hemiplegic migraine (FHM) patients, we examined hippocampal neurotransmission and plasticity in knock-in mice expressing theFHMtype 1 (FHM1) R192Q gain-of function mutation in the CACNA1A gene that encodes the α
U2 - 10.1523/JNEUROSCI.2630-14.2015
DO - 10.1523/JNEUROSCI.2630-14.2015
M3 - Article
SN - 0270-6474
VL - 35
SP - 3397
EP - 3402
JO - The Journal of Neuroscience
JF - The Journal of Neuroscience
IS - 8
ER -
