Modelling fungal hypha tip growth via viscous sheet approximation

T. G. de Jong, J. Hulshof, G. Prokert*

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

In this paper we present a new model for single-celled, non-branching hypha tip growth. The growth mechanism of hypha cells consists of transport of cell wall building material to the cell wall and subsequent incorporation of this material in the wall as it arrives. To model the transport of cell wall building material to the cell wall we follow Bartnicki-Garcia and Gierz in assuming that the cell wall building material is transported in straight lines by an isotropic point source. To model the dynamics of the cell wall, including its growth by new material, we use the approach of Campàs and Mahadevan, which assumes that the cell wall is a thin viscous sheet sustained by a pressure difference. Furthermore, we include a novel equation which models the hardening of the cell wall as it ages. We validate the new model by comparing it to experimental data.

Original languageEnglish
Article number110189
Pages (from-to)1-13
Number of pages13
JournalJournal of Theoretical Biology
Volume492
Early online date5 Feb 2020
DOIs
Publication statusPublished - 7 May 2020

Keywords

  • Cell wall growth
  • Hypha growth
  • Viscous sheet

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