Monitoring of oxidative free radical damage in vivo: analytical aspects

J J Hageman, A Bast, N P E Vermeulen

Research output: Contribution to JournalReview articleAcademicpeer-review


Free radical damage is an important factor in many pathological and toxicological processes. During the last decade a wide range of methods has been developed to determine free radical damage in various biological fluids and at various stages of development. This review offers an overview of the state of the art of monitoring free radical damage in vivo, with special emphasis on the analytical aspects of non-invasive methods.

Original languageEnglish
Pages (from-to)243-293
Number of pages51
JournalChemico-Biological Interactions
Issue number3
Publication statusPublished - May 1992


  • Animals
  • Free Radicals
  • Humans
  • Hydroxides
  • Hydroxyl Radical
  • Monitoring, Physiologic
  • Oxidation-Reduction
  • Oxygen
  • Superoxides
  • Journal Article
  • Review


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