TY - CONF
T1 - Multifunctional optical coherence tomography for endoscopic in-vivo imaging of lungs periphery in asthma patients (Conference Presentation)
AU - Vaselli, Margherita
AU - Feroldi, Fabio
AU - Willemse, Joy
AU - Davidoiu, Valentina
AU - Graefe, Maximilian G. O.
AU - van Iperen, Dirck
AU - de Boer, Johannes F.
PY - 2020/3/7
Y1 - 2020/3/7
N2 - We present a motorized distal scanning endoscope with an outer diameter of 1.35 mm and 52 fps rotation speed for in vivo imaging in the peripheral airways of lungs. Three lung segments of an asthma patient pre and post bronchial thermoplasty (BT) treatment were imaged. Optical coherence tomography (OCT) intensity images, attenuation coefficient (AC) images and polarization sensitive OCT (PS-OCT) images showing both birefringence, optic axis uniformity (OAxU) and optic axis (OA) orientation were extracted from the acquired data. PS-OCT endoscopy visualized airway smooth muscle layer thickness and location pre and post BT treatment as means to predict its effectiveness.
AB - We present a motorized distal scanning endoscope with an outer diameter of 1.35 mm and 52 fps rotation speed for in vivo imaging in the peripheral airways of lungs. Three lung segments of an asthma patient pre and post bronchial thermoplasty (BT) treatment were imaged. Optical coherence tomography (OCT) intensity images, attenuation coefficient (AC) images and polarization sensitive OCT (PS-OCT) images showing both birefringence, optic axis uniformity (OAxU) and optic axis (OA) orientation were extracted from the acquired data. PS-OCT endoscopy visualized airway smooth muscle layer thickness and location pre and post BT treatment as means to predict its effectiveness.
UR - https://www.mendeley.com/catalogue/bd2c460b-5e83-3971-808b-4b07fd4b3cda/
UR - https://www.mendeley.com/catalogue/bd2c460b-5e83-3971-808b-4b07fd4b3cda/
U2 - 10.1117/12.2544318
DO - 10.1117/12.2544318
M3 - Abstract
T2 - SPIE BiOS 2020
Y2 - 1 February 2020 through 6 February 2020
ER -
