Muscle mass and muscle strength are associated with pre- and post-hospitalization falls in older male inpatients: a longitudinal cohort study

Jeanine M. Van Ancum, Mirjam Pijnappels, Nini H. Jonkman, Kira Scheerman, Sjors Verlaan, Carel G.M. Meskers, Andrea B. Maier

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

BACKGROUND: Low muscle mass and strength are highly prevalent in inpatients. It is acknowledged that low muscle mass and strength are associated with falls in community-dwelling older adults, but it is unknown if these muscle measures are also associated with falls in a population of older inpatients. This study aimed to investigate the association between muscle measures and pre- and post-hospitalization falls in older inpatients.

METHODS: An inception cohort of patients aged 70 years and older, admitted to an academic teaching hospital, was included in this study. Muscle mass and hand grip strength were measured at admission using bioelectrical impedance analysis and handheld dynamometry. Pre-hospitalization falls were dichotomized as having had at least one fall in the six months prior to admission. Post-hospitalization falls were dichotomized as having had at least one fall during the three months after discharge. Associations were analysed with logistic regression analysis.

RESULTS: The study cohort comprised 378 inpatients (mean age, SD: 79.7, 6.4 years). Fifty per cent of female and 41% of male patients reported at least one fall prior to hospitalization. Post-hospitalization, 18% of female and 23% of male patients reported at least one fall. Lower muscle mass was associated with post-hospitalization falls, and lower hand grip strength was associated with both pre- and post-hospitalization falls in male, but not in female, patients.

CONCLUSIONS: These findings confirm the likely involvement of muscle mass and strength in the occurrence of pre- and post-hospitalization falls in a population of older inpatients, but only in males.

Original languageEnglish
Article number116
Pages (from-to)1-7
Number of pages7
JournalBMC Geriatrics
Volume18
DOIs
Publication statusPublished - 16 May 2018

Fingerprint

Muscle Strength
Longitudinal Studies
Inpatients
Hospitalization
Cohort Studies
Muscles
Hand Strength
Independent Living
Electric Impedance
Teaching Hospitals
Population
Logistic Models
Regression Analysis

Keywords

  • Accidental Falls
  • Aged
  • Hospitalization
  • Muscle strength
  • Sarcopenia

Cite this

Van Ancum, Jeanine M. ; Pijnappels, Mirjam ; Jonkman, Nini H. ; Scheerman, Kira ; Verlaan, Sjors ; Meskers, Carel G.M. ; Maier, Andrea B. / Muscle mass and muscle strength are associated with pre- and post-hospitalization falls in older male inpatients : a longitudinal cohort study. In: BMC Geriatrics. 2018 ; Vol. 18. pp. 1-7.
@article{d530202030ad44838015e710349444a2,
title = "Muscle mass and muscle strength are associated with pre- and post-hospitalization falls in older male inpatients: a longitudinal cohort study",
abstract = "BACKGROUND: Low muscle mass and strength are highly prevalent in inpatients. It is acknowledged that low muscle mass and strength are associated with falls in community-dwelling older adults, but it is unknown if these muscle measures are also associated with falls in a population of older inpatients. This study aimed to investigate the association between muscle measures and pre- and post-hospitalization falls in older inpatients.METHODS: An inception cohort of patients aged 70 years and older, admitted to an academic teaching hospital, was included in this study. Muscle mass and hand grip strength were measured at admission using bioelectrical impedance analysis and handheld dynamometry. Pre-hospitalization falls were dichotomized as having had at least one fall in the six months prior to admission. Post-hospitalization falls were dichotomized as having had at least one fall during the three months after discharge. Associations were analysed with logistic regression analysis.RESULTS: The study cohort comprised 378 inpatients (mean age, SD: 79.7, 6.4 years). Fifty per cent of female and 41{\%} of male patients reported at least one fall prior to hospitalization. Post-hospitalization, 18{\%} of female and 23{\%} of male patients reported at least one fall. Lower muscle mass was associated with post-hospitalization falls, and lower hand grip strength was associated with both pre- and post-hospitalization falls in male, but not in female, patients.CONCLUSIONS: These findings confirm the likely involvement of muscle mass and strength in the occurrence of pre- and post-hospitalization falls in a population of older inpatients, but only in males.",
keywords = "Accidental Falls, Aged, Hospitalization, Muscle strength, Sarcopenia",
author = "{Van Ancum}, {Jeanine M.} and Mirjam Pijnappels and Jonkman, {Nini H.} and Kira Scheerman and Sjors Verlaan and Meskers, {Carel G.M.} and Maier, {Andrea B.}",
year = "2018",
month = "5",
day = "16",
doi = "10.1186/s12877-018-0812-5",
language = "English",
volume = "18",
pages = "1--7",
journal = "BMC Geriatrics",
issn = "1471-2318",
publisher = "BioMed Central",

}

Muscle mass and muscle strength are associated with pre- and post-hospitalization falls in older male inpatients : a longitudinal cohort study. / Van Ancum, Jeanine M.; Pijnappels, Mirjam; Jonkman, Nini H.; Scheerman, Kira; Verlaan, Sjors; Meskers, Carel G.M.; Maier, Andrea B.

In: BMC Geriatrics, Vol. 18, 116, 16.05.2018, p. 1-7.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Muscle mass and muscle strength are associated with pre- and post-hospitalization falls in older male inpatients

T2 - a longitudinal cohort study

AU - Van Ancum, Jeanine M.

AU - Pijnappels, Mirjam

AU - Jonkman, Nini H.

AU - Scheerman, Kira

AU - Verlaan, Sjors

AU - Meskers, Carel G.M.

AU - Maier, Andrea B.

PY - 2018/5/16

Y1 - 2018/5/16

N2 - BACKGROUND: Low muscle mass and strength are highly prevalent in inpatients. It is acknowledged that low muscle mass and strength are associated with falls in community-dwelling older adults, but it is unknown if these muscle measures are also associated with falls in a population of older inpatients. This study aimed to investigate the association between muscle measures and pre- and post-hospitalization falls in older inpatients.METHODS: An inception cohort of patients aged 70 years and older, admitted to an academic teaching hospital, was included in this study. Muscle mass and hand grip strength were measured at admission using bioelectrical impedance analysis and handheld dynamometry. Pre-hospitalization falls were dichotomized as having had at least one fall in the six months prior to admission. Post-hospitalization falls were dichotomized as having had at least one fall during the three months after discharge. Associations were analysed with logistic regression analysis.RESULTS: The study cohort comprised 378 inpatients (mean age, SD: 79.7, 6.4 years). Fifty per cent of female and 41% of male patients reported at least one fall prior to hospitalization. Post-hospitalization, 18% of female and 23% of male patients reported at least one fall. Lower muscle mass was associated with post-hospitalization falls, and lower hand grip strength was associated with both pre- and post-hospitalization falls in male, but not in female, patients.CONCLUSIONS: These findings confirm the likely involvement of muscle mass and strength in the occurrence of pre- and post-hospitalization falls in a population of older inpatients, but only in males.

AB - BACKGROUND: Low muscle mass and strength are highly prevalent in inpatients. It is acknowledged that low muscle mass and strength are associated with falls in community-dwelling older adults, but it is unknown if these muscle measures are also associated with falls in a population of older inpatients. This study aimed to investigate the association between muscle measures and pre- and post-hospitalization falls in older inpatients.METHODS: An inception cohort of patients aged 70 years and older, admitted to an academic teaching hospital, was included in this study. Muscle mass and hand grip strength were measured at admission using bioelectrical impedance analysis and handheld dynamometry. Pre-hospitalization falls were dichotomized as having had at least one fall in the six months prior to admission. Post-hospitalization falls were dichotomized as having had at least one fall during the three months after discharge. Associations were analysed with logistic regression analysis.RESULTS: The study cohort comprised 378 inpatients (mean age, SD: 79.7, 6.4 years). Fifty per cent of female and 41% of male patients reported at least one fall prior to hospitalization. Post-hospitalization, 18% of female and 23% of male patients reported at least one fall. Lower muscle mass was associated with post-hospitalization falls, and lower hand grip strength was associated with both pre- and post-hospitalization falls in male, but not in female, patients.CONCLUSIONS: These findings confirm the likely involvement of muscle mass and strength in the occurrence of pre- and post-hospitalization falls in a population of older inpatients, but only in males.

KW - Accidental Falls

KW - Aged

KW - Hospitalization

KW - Muscle strength

KW - Sarcopenia

UR - http://www.scopus.com/inward/record.url?scp=85047132994&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047132994&partnerID=8YFLogxK

U2 - 10.1186/s12877-018-0812-5

DO - 10.1186/s12877-018-0812-5

M3 - Article

VL - 18

SP - 1

EP - 7

JO - BMC Geriatrics

JF - BMC Geriatrics

SN - 1471-2318

M1 - 116

ER -