TY - JOUR
T1 - Mx Scripts Library: Structural Equation Modeling Scripts for Twin and Family Data
AU - Posthuma, D.
AU - Boomsma, D.I.
PY - 2005
Y1 - 2005
N2 - Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/ or longitudinal data, incorporate sex differences in parameter estimates, and model the effects of measured environment, candidate genes or DNA marker data. We introduce a web-based library ( http://www.psy.vu.nl/mxbib ) of scripts for uni- and multivariate genetic epidemiological analyses, as well as for linkage and genetic association tests. The scripts are written to be used with the freely available software package Mx and provide a flexible and uniform approach to the analysis of data from relatives. © 2005 Springer Science+Business Media, Inc.
AB - Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/ or longitudinal data, incorporate sex differences in parameter estimates, and model the effects of measured environment, candidate genes or DNA marker data. We introduce a web-based library ( http://www.psy.vu.nl/mxbib ) of scripts for uni- and multivariate genetic epidemiological analyses, as well as for linkage and genetic association tests. The scripts are written to be used with the freely available software package Mx and provide a flexible and uniform approach to the analysis of data from relatives. © 2005 Springer Science+Business Media, Inc.
UR - https://www.scopus.com/pages/publications/20544465891
UR - https://www.scopus.com/inward/citedby.url?scp=20544465891&partnerID=8YFLogxK
U2 - 10.1007/s10519-005-2791-5
DO - 10.1007/s10519-005-2791-5
M3 - Article
SN - 0001-8244
VL - 35
SP - 499
EP - 505
JO - Behavior Genetics
JF - Behavior Genetics
IS - 4
ER -
