N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist

R. Kitbunnadaj; T. Hashimoto; E. Poli; O.P. Zuiderveld; A. Menozzi; R. Hidaka; I.J.P. de Esch; R.A. Bakker; W.M.P.B. Menge; A. Yamatodani; G. Coruzzi; H. Timmerman; R. Leurs

doi:10.1021/jm049475h

N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist

R. Kitbunnadaj, T. Hashimoto, E. Poli, O.P. Zuiderveld, A. Menozzi, R. Hidaka, I.J.P. de Esch, R.A. Bakker, W.M.P.B. Menge, A. Yamatodani, G. Coruzzi, H. Timmerman, R. Leurs

Chemistry and Pharmaceutical Sciences

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

In this study, we continue our efforts toward the development of potent and highly selective histamine H

Original language	English
Pages (from-to)	2100-7
Journal	Journal of Medicinal Chemistry
Volume	48
Issue number	6
DOIs	https://doi.org/10.1021/jm049475h
Publication status	Published - 2005

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Kitbunnadaj, R., Hashimoto, T., Poli, E., Zuiderveld, O. P., Menozzi, A., Hidaka, R., de Esch, I. J. P., Bakker, R. A., Menge, W. M. P. B., Yamatodani, A., Coruzzi, G., Timmerman, H., & Leurs, R. (2005). N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist. Journal of Medicinal Chemistry, 48(6), 2100-7. https://doi.org/10.1021/jm049475h

@article{c094febc11574c77b66b5651ab501053,

title = "N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist",

abstract = "In this study, we continue our efforts toward the development of potent and highly selective histamine H",

author = "R. Kitbunnadaj and T. Hashimoto and E. Poli and O.P. Zuiderveld and A. Menozzi and R. Hidaka and {de Esch}, I.J.P. and R.A. Bakker and W.M.P.B. Menge and A. Yamatodani and G. Coruzzi and H. Timmerman and R. Leurs",

year = "2005",

doi = "10.1021/jm049475h",

language = "English",

volume = "48",

pages = "2100--7",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "6",

}

Kitbunnadaj, R, Hashimoto, T, Poli, E, Zuiderveld, OP, Menozzi, A, Hidaka, R, de Esch, IJP, Bakker, RA, Menge, WMPB, Yamatodani, A, Coruzzi, G, Timmerman, H & Leurs, R 2005, 'N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist', Journal of Medicinal Chemistry, vol. 48, no. 6, pp. 2100-7. https://doi.org/10.1021/jm049475h

TY - JOUR

T1 - N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist

AU - Kitbunnadaj, R.

AU - Hashimoto, T.

AU - Poli, E.

AU - Zuiderveld, O.P.

AU - Menozzi, A.

AU - Hidaka, R.

AU - de Esch, I.J.P.

AU - Bakker, R.A.

AU - Menge, W.M.P.B.

AU - Yamatodani, A.

AU - Coruzzi, G.

AU - Timmerman, H.

AU - Leurs, R.

PY - 2005

Y1 - 2005

N2 - In this study, we continue our efforts toward the development of potent and highly selective histamine H

AB - In this study, we continue our efforts toward the development of potent and highly selective histamine H

U2 - 10.1021/jm049475h

DO - 10.1021/jm049475h

M3 - Article

SN - 0022-2623

VL - 48

SP - 2100

EP - 2107

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 6

ER -

N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist

Abstract

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