Naphthoquinone derivates exert their antitrypanosomal activity via a multi-target mechanism.

S. Pieretti, J.R. Haanstra, M. Mazet, R. Perozzo, C. Bergamini, F. Prati, R. Fato, G. Lenaz, G. Capranico, R. Brun, B.M. Bakker, P.A.M. Michels, L. Scapozza, M.L. Bolognesi, A. Cavalli

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background and Methodology: Recently, we reported on a new class of naphthoquinone derivatives showing a promising anti-trypanosomatid profile in cell-based experiments. The lead of this series (B6, 2-phenoxy-1,4-naphthoquinone) showed an ED
Original languageEnglish
Article numbere2012
Pages (from-to)1-12
JournalPLoS Neglected Tropical Diseases
Volume7
DOIs
Publication statusPublished - 2013

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