Neurodegeneration: New Road Leads Back to the Synapse

P. Heutink, M. Verhage

Research output: Contribution to JournalArticleAcademicpeer-review


Much of Parkinson's research over the last decade has focused on cellular stress as a candidate mechanism. In this issue of Neuron, a new study by Matta et al. (2012) addressing the biological functions of the Parkinson's gene LRRK2 now identifies a presynaptic substrate, homing in on the idea that synapse loss might be a central early aspect of neurodegeneration. © 2012 Elsevier Inc.
Original languageEnglish
Pages (from-to)935-938
Issue number6
Publication statusPublished - 2012


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