New-generation positional therapy in patients with positional central sleep apnea

L.B.L. Benoist, P.E. Vonk, N. de Vries, H.C.J.P. Janssen, J. Verbraecken

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Purpose To evaluate the effect of a sleep position trainer (SPT) in patients with positional central sleep apnea (PCSA).
Methods A multicentre cohort study was conducted. Patients with symptomatic PCSA were included. Effectiveness, compliance and quality of life were assessed at 1- and 6-month follow-up.
Results Sixteen patients were included. Median AHI dropped from 23.4/h [12.9–31.2] to 11.5/h [7.2–24.5] (p = 0.044) after 1-month SPT therapy and in patients who continued treatment, median AHI further decreased after 6 months to 9.7/h [3.4–27.6] (p = 0.075). Median percentage of supine sleep decreased significantly from 37.6 [17.2–51.8] to 6.7 [0.7–22.8] (p < 0.001), after 1 month, and to 6.8 [0.7–22.1] (p = 0.001), after 6 months. Mean compliance over 1 and 6 months was 78.6 ± 35.3 and 66.0 ± 33.3%, respectively. Epworth Sleepiness Scale at baseline was 9.5 [3.3–11.8] and did not significantly decrease after 1 month (11.0 [3.0–13.0]) and 6 months (4.0 [3.0–10.5]) follow-up. Functional Outcomes of Sleep Questionnaire remained stable within the first month. However, after 6 months, there was a significant improvement compared to baseline values, 15.9 [11.9–18.4] vs. 17.8 [14.3–19.2]; p = 0.030.
Conclusion This is the first study on effects of positional therapy with a new-generation smart device in patients with PCSA after 1 and 6 months of follow-up. Results of this study show that the SPT is effective in reducing AHI and central AI, feasible in PCSA, and is associated with symptomatic improvement. While the working mechanism behind this effect remains speculative, the effect is positive and considerable.

Original languageEnglish
Pages (from-to)2611-2619
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume276
Issue number9
DOIs
Publication statusPublished - Sept 2019

Bibliographical note

Export Date: 17 October 2019

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