Nonlinear elasticity of stiff biopolymers connected by flexible linkers

K. E. Kasza; G.H. Koenderink; Y.C. Lin; C.P. Broedersz; W. Messner; F. Nakamura; T. P. Stossel; F.C. Mac Kintosh; D. A. Weitz

doi:10.1103/PhysRevE.79.041928

Nonlinear elasticity of stiff biopolymers connected by flexible linkers

K. E. Kasza, G.H. Koenderink, Y.C. Lin, C.P. Broedersz, W. Messner, F. Nakamura, T. P. Stossel, F.C. Mac Kintosh, D. A. Weitz

Physics of Living Systems

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Abstract

Networks of the biopolymer actin, cross-linked by the compliant protein filamin, form soft gels. They can, however, withstand large shear stresses due to their pronounced nonlinear elastic behavior. The nonlinear elasticity can be controlled by varying the number of cross-links per actin filament. We propose and test a model of rigid filaments decorated by multiple flexible linkers that is in quantitative agreement with experiment. This allows us to estimate loads on individual cross-links, which we find to be less than 10 pN. © 2009 The American Physical Society.

Original language	English
Pages (from-to)	041928
Journal	Physical Review E
Volume	79
Issue number	4 Pt 1
DOIs	https://doi.org/10.1103/PhysRevE.79.041928
Publication status	Published - 2009

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title = "Nonlinear elasticity of stiff biopolymers connected by flexible linkers",

abstract = "Networks of the biopolymer actin, cross-linked by the compliant protein filamin, form soft gels. They can, however, withstand large shear stresses due to their pronounced nonlinear elastic behavior. The nonlinear elasticity can be controlled by varying the number of cross-links per actin filament. We propose and test a model of rigid filaments decorated by multiple flexible linkers that is in quantitative agreement with experiment. This allows us to estimate loads on individual cross-links, which we find to be less than 10 pN. {\textcopyright} 2009 The American Physical Society.",

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AU - Kasza, K. E.

AU - Koenderink, G.H.

AU - Lin, Y.C.

AU - Broedersz, C.P.

AU - Messner, W.

AU - Nakamura, F.

AU - Stossel, T. P.

AU - Mac Kintosh, F.C.

AU - Weitz, D. A.

N1 - Times Cited: 0

PY - 2009

Y1 - 2009

N2 - Networks of the biopolymer actin, cross-linked by the compliant protein filamin, form soft gels. They can, however, withstand large shear stresses due to their pronounced nonlinear elastic behavior. The nonlinear elasticity can be controlled by varying the number of cross-links per actin filament. We propose and test a model of rigid filaments decorated by multiple flexible linkers that is in quantitative agreement with experiment. This allows us to estimate loads on individual cross-links, which we find to be less than 10 pN. © 2009 The American Physical Society.

AB - Networks of the biopolymer actin, cross-linked by the compliant protein filamin, form soft gels. They can, however, withstand large shear stresses due to their pronounced nonlinear elastic behavior. The nonlinear elasticity can be controlled by varying the number of cross-links per actin filament. We propose and test a model of rigid filaments decorated by multiple flexible linkers that is in quantitative agreement with experiment. This allows us to estimate loads on individual cross-links, which we find to be less than 10 pN. © 2009 The American Physical Society.

U2 - 10.1103/PhysRevE.79.041928

DO - 10.1103/PhysRevE.79.041928

M3 - Article

SN - 1539-3755

VL - 79

SP - 041928

JO - Physical Review E

JF - Physical Review E

IS - 4 Pt 1

ER -

Nonlinear elasticity of stiff biopolymers connected by flexible linkers

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