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Novel nirK cluster genes in Nitrosomonas europaea are required for NirK-dependent tolerance to nitrite

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Nitrite reductase (NirK) of Nitrosomonas europaea confers tolerance to nitrite (NO2-). The nirK gene is clustered with three genes of unknown physiological function: ncgABC. At present, this organization is unique to nitrifying bacteria. Here we report that the ncgABC gene products facilitate NirK-dependent NO2- tolerance by reversing the negative physiological effect that is associated with the activity of NirK in their absence. We hypothesize that the ncg gene products are involved in the detoxification of nitric oxide that is produced by NirK.

    Original languageEnglish
    Pages (from-to)6849-51
    Number of pages3
    JournalJournal of Bacteriology
    Volume187
    Issue number19
    DOIs
    Publication statusPublished - Oct 2005

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 6 - Clean Water and Sanitation
      SDG 6 Clean Water and Sanitation

    Keywords

    • Genes, Bacterial
    • Multigene Family
    • Mutation
    • Nitric Oxide
    • Nitrite Reductases
    • Nitrites
    • Nitrosomonas europaea
    • Operon
    • Oxidoreductases
    • Journal Article
    • Research Support, Non-U.S. Gov't

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