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Objective and subjective suicidal intent are differentially associated with attempt lethality based on age of onset of suicidal behavior

  • Anna Szücs
  • , Michelle A. Perry-Falconi
  • , Emma J. O'Brien
  • , John G. Keilp
  • , Jeffrey A. Bridge
  • , Andrea B. Maier
  • , Hanga Galfalvy
  • , Katalin Szanto

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Predicting the medical seriousness, or lethality, of suicide attempts remains challenging for clinicians, as impulsive and planned attempts can both be fatal and risk may vary with age and suicidal intent. We investigated whether attempt lethality is driven by practical preparedness (objective suicidal intent) and/or psychological resolve (subjective suicidal intent) and whether these associations vary with age of onset of suicidal behavior. The study used a cross-sectional lifespan sample (N = 95; age range 16-76 years) with current depression and recent suicidal behavior (≤ 5 years). Linear regression models indicated that older age of onset of suicidal behavior (B = 0.86, SE = 0.20, p < 0.001), and both higher objective intent (B = 0.69, SE = 0.19, p < 0.001) and subjective intent (B = 0.50, SE = 0.20, p = 0.014) were associated with more severe lethality at the most recent attempt, although the association with subjective intent was driven by its shared portion with objective intent. The association between objective intent and lethality was stronger with older age of onset (interaction B = 0.75, SE = 0.20, p < 0.001), whereas the association between subjective intent and lethality was stronger with younger age of onset (interaction B = - 0.42, SE = 0.20, p = 0.036). Our findings suggest that contextualizing suicidal intentions with age of onset, rather than age at the current suicidal crisis, can help clinicians better appraise suicide risk.

Original languageEnglish
Article number5621
Pages (from-to)1-10
Number of pages10
JournalScientific Reports
Volume15
Early online date15 Feb 2025
DOIs
Publication statusPublished - 2025

Bibliographical note

Publisher Copyright:
© 2025. The Author(s).

Funding

This work was supported by the American Foundation for Suicide Prevention [LSRG-0\u2013007\u201313 to JGK, JAB, and KSz] as well as the National Institute of Mental Health [R01MH085651 to KSz], and by internal funds to the National University of Singapore: Division of Family Medicine Research Capabilities Building Budget [NUHSRO/2022/049/NUSMed/DFM].

FundersFunder number
American Foundation for Suicide PreventionLSRG-0–007–13
National Institute of Mental HealthR01MH085651
National University of SingaporeNUHSRO/2022/049/NUSMed/DFM

    Keywords

    • Age
    • Attempt lethality
    • Lifespan
    • Suicidal behavior
    • Suicidal intent
    • Suicide attempt

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