Objectively measured sleep and body mass index: a prospective bidirectional study in middle-aged and older adults

Chantal M. Koolhaas, Desana Kocevska, Bart H.W. te Lindert, Nicole S. Erler, Oscar H. Franco, Annemarie I. Luik*, Henning Tiemeier

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background: In recent years, short sleep has been increasingly recognized as a risk factor for obesity. However, current evidence has so far been limited to cross-sectional studies or longitudinal studies using self-reported sleep. Therefore, we explored the directionality of the association between objectively measured sleep and body mass index (BMI). Methods: The study consists of 1031 participants from the general population (52% women, 45–91 years at baseline). Sleep, BMI and waist circumference (WC) were measured twice across a follow-up of six years. BMI and WC were measured at the research center. Total sleep time (TST, hrs), sleep onset latency (SOL, min), sleep efficiency (SE, %) and wake after sleep onset (WASO, min) were estimated by a wrist-worn actigraph. In addition, cross-sectional and longitudinal associations in both directions were explored. Results: An hour shorter TST was cross-sectionally associated with approximately 0.5 kg/m 2 higher BMI. Longitudinally, longer TST and higher SE were associated with lower BMI (β TST = −0.75, 95% CI: −1.08, −0.42; β SE = −0.04, 95% CI: −0.08, −0.01). Conversely, one kg/m 2 higher BMI was prospectively associated with 0.02 h shorter TST (95% CI: −0.03, −0.01), and this association was more pronounced over time. Results from analyses with WC were in line with those of BMI. Conclusions: This is the first study to explore bidirectionality in the association between objectively measured sleep and BMI in a large population of middle-aged and older adults. Indices of poor sleep were associated with higher and less stable BMI across time. Conversely, a high BMI was associated with a decrease in sleep duration. This confirms that the relation between sleep and body size is bidirectional, and changes in either sleep or BMI are likely to co-occur with changes in health through multiple pathways.

Original languageEnglish
Pages (from-to)43-50
Number of pages8
JournalSleep Medicine
Volume57
DOIs
Publication statusPublished - 1 May 2019
Externally publishedYes

Keywords

  • Actigraphy
  • Bidirectional association
  • Body mass index
  • Sleep

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