Obsessive Compulsive Disorder: A Pathology of Self-Confidence?

Julian Kiverstein*, Erik Rietveld, Heleen A. Slagter, Damiaan Denys

*Corresponding author for this work

Research output: Contribution to JournalShort surveyAcademicpeer-review


A striking change OCD patients repeatedly describe following treatment with deep brain stimulation (DBS)of the ventral anterior limb of internal capsule (vALIC)is an immediate increase in self-confidence. We show how the DBS-induced changes in self-confidence reported by our patients can be understood neurocognitively in terms of active inference.

Original languageEnglish
Pages (from-to)369-372
Number of pages4
JournalTrends in Cognitive Sciences
Issue number5
Early online date3 Apr 2019
Publication statusPublished - 1 May 2019


We would like to thank Mark Miller, Judy Luigjes, and three anonymous referees for very helpful feedback on this article. J.K. and E.R. are supported by a European Research Council Starting Grant (679190) awarded to E.R. and by an Amsterdam Brain and Cognition Research Grant (awarded to D.D., E.R., and H.A.S.). H.A.S. is supported by an ERC Starting Grant (679399) awarded to H.A.S.

FundersFunder number
Horizon 2020 Framework Programme679190, 679399
European Research Council


    • active inference
    • affordances
    • anxiety
    • deep brain stimulation
    • field of affordances
    • OCD
    • precision estimation
    • self-confidence
    • ventral striatum


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